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基于“阳明脉衰-肾气衰”辨治迟发性性腺功能减退症

Differentiation and treatment of late-onset hypogonadism based on the theory of"decline of Yangming meridian-kidney qi deficiency"
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摘要 迟发性性腺功能减退症(late-onset hypogonadism,LOH)是发生于中老年男性的常见病。中医药治疗可有效改善LOH症状,中医认为在LOH发病过程中,“阳明脉衰”驱动“肾气衰”;脂肪组织(adipose tissue,AT)功能障碍可能是阳明脉衰、脾失健运的重要表现。治疗LOH应当兼顾脾肾,养后天以滋先天,可采用健脾益气、滋阴补肾,温肾暖脾、益气助阳,健脾补肾、利湿化浊之法,调理阳明、培补肾气。 Late-onset hypogonadism(LOH)is a common condition in middle-aged and elderly men that severely affects their quality of life.Traditional Chinese medicine(TCM)can effectively improve LOH symptoms.TCM theory holds that in the pathogenesis of LOH,"decline of the Yangming meridian"drives"kidney qi deficiency".Dysfunction of adipose tissue(AT)may be an important manifestation of Yangming meridian decline and spleen dysfunction.Treatment of LOH should address both the spleen and kidney,nourishing the acquired constitution to support the innate constitution.Methods such as invigorating the spleen and benefiting qi,nourishing yin and tonifying the kidney,warming the kidney and spleen,benefiting qi to assist yang,strengthening the spleen and kidney,and promoting diuresis to remove turbidity can be used to regulate the Yangming meridian and reinforce kidney qi.
作者 程皓洋 张小燕 曹得中 罗成龙 张琪 张思政 焦拥政 CHENG Haoyang;ZHANG Xiaoyan;CAO Dezhong;LUO Chenglong;ZHANG Qi;ZHANG Sizheng;JIAO Yongzheng(Department of Andrology,Guang'anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100053,China;Department of Dermatology,Xi'an Hospital of Traditional Chinese Medicine,Xi'an 710001;Department of Traditional Chinese Medicine,First People's Hospital of Dongcheng District,Beijing 100077)
出处 《北京中医药》 2025年第6期773-777,共5页 Beijing Journal of Traditional Chinese Medicine
基金 国家自然科学基金项目(82074446,82474523) 中国中医科学院科技创新工程项目(CI2021A02202)。
关键词 迟发性性腺功能减退 阳明脉衰 肾气衰 健脾益肾 late-onset hypogonadism decline of Yangming meridian deficiency of kidney qi invigorating the spleen and tonifying the kidney
作者简介 程皓洋,男,29岁,博士研究生。研究方向:泌尿男科疾病的中西医结合基础与临床研究;通信作者:焦拥政,E-mail:yzhjiao@126.com。
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