摘要
连翘为木犀科植物连翘Forsythia suspensa(Thunb.)Vahl的干燥果实,具有清热解毒、消肿散结等功效。连翘主要药用成分包括木脂素类、苯乙醇苷类、萜类、黄酮类、酚酸类等,具有抗炎、抗菌和抗肿瘤等活性。通过查阅文献,对连翘主要化学成分、抗肿瘤作用及机制进行综述,以期为连翘的开发利用提供参考。
Forsythiae Fructus,the dried fruit of Forsythia suspensa(Thunb.)Vahl(Oleaceae family),possesses pharmacological effects including heat-clearing,detoxification,swelling reduction,and mass dispersion.The main medicinal components of Forsythiae Fructus include lignans,phenylethanolic glycosides,terpenes,flavonoids,and phenolic acids,which exhibit anti-inflammatory,antibacterial,and anti-tumor activities.This review systematically summarizes the chemical composition,antitumor efficacy,and molecular mechanisms of Forsythiae Fructus,providing valuable insights for its further pharmaceutical development and clinical application.
作者
吴永娜
薛怡萌
李亚鹏
屈沛佳
靳智博
滕文龙
牛颜冰
WU Yongna;XUE Yimeng;LI Yapeng;QU Peijia;JIN Zhibo;TENG Wenlong;NIU Yanbing(College of Life Sciences,Shanxi Agricultural University,Jinzhong 030600,China)
出处
《中国现代中药》
2025年第7期1354-1364,共11页
Modern Chinese Medicine
基金
财政部和农业农村部:国家现代农业产业技术体系资助项目
山西省自然科学基金项目(202203021212471)
山西农业大学博士科研启动项目(J142202205)。
关键词
连翘
连翘苷
连翘酯苷
连翘酯素
抗肿瘤
Forsythiae Fructus
forsythin
forsythiaside
phillygenin
anti-tumor
作者简介
通信作者:牛颜冰,教授,研究方向:药用植物遗传学,E-mail:niuyanbingbest@163.com。
