摘要
目的探究祛瘀化痰汤联合常规西药治疗痰瘀互结型冠状动脉粥样硬化性心脏病(以下简称“冠心病”)心绞痛的临床效果。方法将符合纳入标准的62例痰瘀互结型冠心病心绞痛患者随机分为观察组和对照组,各31例。对照组予常规西药治疗,观察组在对照组基础上予祛瘀化痰汤治疗,观察两组临床效果、中医证候积分、血脂[胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)]水平。结果观察组总有效率93.55%(29/31)高于对照组的70.97%(22/31)(P<0.05)。治疗后,两组中医证候积分以及TC、TG、LDL-C、HDL-C水平均较治疗前改善(P<0.05),且观察组均优于对照组(P<0.05)。结论祛瘀化痰汤联合常规西药治疗痰瘀互结型冠心病心绞痛的临床效果明显优于常规西药,且能够改善患者临床症状。其治疗机制可能为通过降低TC、TG、LDL-C水平和升高HDL-C水平,使机体血液黏稠度降低,扩张冠状动脉,从而改善心肌供血。
Objective To study the clinical efficacy of Quyu Huatan decoction combined with conventional Western medicine in the treatment of angina pectoris of coronary heart disease with intermingled phlegm and blood stasis type.Methods Sixty two patients with angina pectoris of coronary heart disease of phlegm and blood stasis type who met the inclusion criteria were randomly divided into the observation group and the control group,with 31 cases in each group.The control group was treated with conventional Western medicine.The observation group was given Quyu Huatan decoction on the basis of the control group.The overall clinical efficacy,traditional Chinese medicine(TCM)syndrome score,cholesterol(TC),triglyceride(TG),low-density lipoprotein(LDL-C)and high-density lipoprotein(HDL-C)between the two groups were observed.Results The total effective rate in the observation group was 93.55%(29/31),which was higher than that in the control group(70.97%,22/31),and the difference was statistically significant(P<0.05).After treatment,the TCM syndrome scores and the levels of TC,TG,LDL-C and HDL-C of the two groups of patients were improved compared with those before the treatment(P<0.05),and the observation group was better than the control group(P<0.05).Conclusion The clinical effect of Quyu Huatan decoction combined with conventional Western medicine in the treatment of angina pectoris of coronary heart disease with intermingled phlegm and blood stasis type is significantly better than that of the control group,and it can improve the clinical symptoms of patients.Its therapeutic mechanism may be to reduce the levels of TC,TG,LDL-C and increase the level of HDL-C,reduce the blood viscosity of the body,dilate the coronary arteries,and thereby improve myocardial blood supply.
作者
龚芳
符凯
熊艳萍
田志宁
王超
李群
GONG Fang;FU Kai;XIONG Yanping;TIAN Zhining;WANG Chao;LI Qun(Department of Cardiology,Zhangjiajie Hospital of Traditional Chinese Medicine,Hunan Province,Zhangjiajie 427000,China)
出处
《中国中医药现代远程教育》
2025年第9期165-168,共4页
Chinese Medicine Modern Distance Education of China
基金
湖南省中医药管理局青年课题项目【No.202113】。
关键词
胸痹心痛
冠心病心绞痛
痰瘀互结证
祛瘀化痰汤
中西医结合疗法
chest stuffiness and pains
angina pectoris of coronary heart disease
intermingled phlegm and blood stasis syndrome
Quyu Huatan decoction
therapy of integrated traditional Chinese and Western medicine
作者简介
通信作者:李群,584834980@qq.com。
