摘要
中国食管癌疾病负担居全球首位,发病率地区差异显著。四川省作为食管癌高发地区,面临更加复杂严峻的现状。晚期食管鳞状细胞癌一线免疫治疗联合化疗临床应用广泛,但免疫耐药后疾病进展的治疗尚无统一标准和共识,各级医院的治疗方案相对杂乱。鉴于此,四川省抗癌协会食管癌专业委员会组织省内食管癌研究领域的多学科专家,参考国内外指南、共识和最新循证医学研究证据,结合临床实践经验,共同制订了本共识,以期为临床医师提供科学、规范的指导,进一步提高晚期食管鳞状细胞癌患者的治疗效果和生命质量,推动四川省食管癌诊疗水平的提升。
The disease burden of esophageal cancer in China ranks first in the world,with significant regional differences in incidence.Sichuan province is facing a more complicated and severe situation,with a high incidence of esophageal cancer.Although first-line immunotherapy combined with chemotherapy for advanced esophageal squamous cell carcinoma has been widely used clinically,but there is no unified standard and consensus on the treatment of disease progression after immune resistance.The treatment strategy of citylevel hospitals is somewhat disordered.In light of this,the Esophageal Cancer Professional Committee of the Sichuan Anti-Cancer Association,in conjunction with multidisciplinary experts in the field of esophageal cancer research in Sichuan province,has developed this consensus.The consensus refers to domestic and foreign guidelines,consensus,and the latest evidence-based clinical evidence,combined with clinical practice experience,with the aim of providing scientific and standardized guidance for clinicians.It is hoped to further improve the treatment outcomes and quality of life for patients with advanced esophageal squamous cell carcinoma and promote the advancement of esophageal cancer diagnosis and treatment in Sichuan province.
作者
四川省抗癌协会食管癌专业委员会
李娜
王奇峰
Esophageal Cancer Professional Committee of the Sichuan Anti-Cancer Association;Li Na;Wang Qifeng(不详;Cancer Center of Suining Central Hospital,Sichuan Province,Suining 629000,China;Department of Radiotherapy,Radiation Oncology Key Laboratory of Sichuan Province,Sichuan Clinical Research Center for Cancer,Sichuan Cancer Hospital&Institute,Sichuan Cancer Center,Affiliated Cancer Hospital of University of Electronic Science and Technology of China,Chengdu 610041,China)
出处
《国际肿瘤学杂志》
2025年第5期273-281,共9页
Journal of International Oncology
基金
川渝地区食管癌精准防控及诊疗体系建立与临床推广项目(2023YFS0488)。
关键词
食道鳞癌
免疫检查点抑制剂
抗药性
疾病恶化
治疗策略
专家共识
Esophageal squamous cell carcinoma
Immune checkpoint inhibitors
Drug resistance
Disease progression
Treatment strategy
Expert consensus
作者简介
通信作者:李娜,四川省遂宁市中心医院肿瘤中心,遂宁629000,Email:1500921245@qq.com;通信作者:王奇峰,放疗科,放射肿瘤学四川省重点实验室,四川省肿瘤临床医学研究中心,四川省肿瘤医院·研究所,四川省癌症防治中心,电子科技大学附属肿瘤医院,成都610041,Email:wangqifeng@scszlyy.org.cn。
