摘要
铁死亡是一种新的调节性细胞死亡方式,其本质是铁代谢失衡以及脂质过氧化物的积累。鸢尾素通过抑制铁死亡改善相关病情的观点已经得到证实。概述铁死亡的相关机制,综述鸢尾素通过抑制铁死亡改善相关病情的研究现状,为治疗铁死亡参与的相关疾病提供新病情思路。
Ferroptosis,a new modality of regulated cell death,is essentially an imbalance in iron metabolism as well as accu⁃mulation of lipid peroxides.The idea that irisin ameliorates related diseases by inhibiting ferroptosis has been demonstrated.The relevant mechanisms of ferroptosis are outlined and the current research status mainly on irisin ameliorating related diseases by in⁃hibiting ferroptosis is reviewed,which will provide new therapeutic ideas for related diseases involved in ferroptosis.
作者
南春晓
王珊
李鑫
王佳城
刘娟
庞伟
Nan Chunxiao;Wang Shan;Li Xin(Jiamusi University School of Rehabilitation Medicine,Jiamusi,Heilongjiang,154700,China)
出处
《黑龙江医学》
2025年第14期1787-1789,共3页
Heilongjiang Medical Journal
基金
黑龙江省自然科学基金项目(LH2022H092)。
作者简介
通信作者:庞伟,E-mail:pangwei76@aliyun.com。
