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PKEP与PKRP治疗良性前列腺增生伴高血压的疗效比较

Observation on the efficacy of transurethral plasmakinetic enucleation of the prostate and transurethral bipolar plasmakinetic resection of the prostate in the treatment of benign prostatic hyperplasia and hypertension
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摘要 目的:探讨比较经尿道等离子前列腺剜除术(PKEP)与经尿道双极等离子前列腺电切术(PKRP)对良性前列腺增生(BPH)伴高血压患者的治疗效果。方法:回顾性分析2021年4月至2024年4月南通大学附属南京江北医院收治的110例BPH伴高血压患者的临床资料,其中55例行PKEP术(PKEP组),55例行PKRP术(PKRP组)。记录两组患者的术中出血量、前列腺切除重量、手术时间、住院时间及手术并发症发生情况;比较两组患者术前及术后1个月的最大尿流率(MFR)、残余尿量(RUV)、平均尿流率(AFR)、国际前列腺症状评分(IPSS)、生活质量(QOL)评分,并记录围手术期的血压变化情况。结果:PKEP组的术中出血量、手术时间、住院时间均低于PKRP组,前列腺切除重量大于PKRP组,差异均有统计学意义(均P<0.05);术后1个月,两组患者的MFR、AFR水平均较术前提高,RUV水平、IPSS、QOL评分均较术前降低,且PKEP组较PKRP组更为明显,差异均有统计学意义(均P<0.05);PKEP组的手术并发症发生率低于PKRP组[5.45%(3/55)vs.21.82%(12/55),P<0.05];两组围手术期血压水平比较,差异无统计学意义(P>0.05)。结论:与PKRP比较,PKEP治疗BPH伴高血压患者的疗效更确切、操作更快速、术后恢复更快,对排尿功能的改善更明显,且并发症更少、安全性更高,但二者均不影响患者围手术期的血压水平变化。 Objective:To observe the therapeutic effects of transurethral plasmakinetic enucleation of the prostate(PKEP)and transurethral bipolar plasmakinetic resection of the prostate(PKRP)in patients with benign prostatic hyperplasia(BPH)and hypertension.Methods:The clinical data of 110 patients with BPH accompanied with hypertension admitted to Nanjing Jiangbei Hospital Affiliated to Nantong University from April 2021 to April 2024 were retrospectively analyzed,of which 55 patients underwent PKEP(PKEP group)and 55 patients underwent PKRP(PKRP group).Intraoperative blood loss,prostatectomy weight,operation time,hospital stay and postoperative complications were recorded in the two groups.The maximum urine flow rate(MFR),residual urine volume(RUV),average urine flow rate(AFR),International Prostate Symptom Score(IPSS)and quality of life(QOL)scores of the two groups before and after surgery were compared,and perioperative blood pressure levels were recorded.Results:The intraoperative blood loss,operation time,and hospitalization time of the PKEP group were lower than those of the PKRP group,and the prostatectomy weight was greater than that of the PKRP group(all P<0.05).One month after surgery,the MFR and AFR levels of the two groups increased,and the RUV levels,IPSS,and QOL scores decreased,and it was more obvious in PKEP group(all P<0.05).The incidence of surgical complications in PKEP group was lower than that in PKRP group[5.45%(3/55)vs.21.82%(12/55),P<0.05].There was no significant difference in perioperative blood pressure between the two groups(P>0.05).Conclusions:Compared with PKRP,PKEP has accurate efficacy,rapid operation,faster postoperative recovery,more obvious improvement in urinary function,fewer complications,and higher safety in treating BPH with hypertension,but neither of them affects the changes in patients'perioperative blood pressure levels.
作者 许飞 杨元强 徐建华 胡志凯 李巍 李文光 Xu Fei;Yang Yuanqiang;Xu Jianhua;Hu Zhikai;Li Wei;Li Wenguang(Nantong University,Nantong 226000,China;Department of Urology,Nanjing Jiangbei Hospital Affiliated to Nantong University,Nanjing 210000,China;Department of Urology,Affiliated Hospital of Nantong University,Nantong 226000,China)
出处 《国际泌尿系统杂志》 2025年第3期29-33,共5页 International Journal of Urology and Nephrology
关键词 前列腺增生 高血压 等离子前列腺剜除术 双极等离子前列腺电切术 Prostatic Hyperplasia Hypertension Plasmakinetic Enucleation of Prostate Plasmakinetic Resection of the Prostate
作者简介 通信作者:李文光,Email:ntlwg@ntu.edu.cn。
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