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SLC7A11 transporter maintains critical nonessential amino acids levels to hamper ferroptosis during MASLD progression

SLC7A11严控非必需氨基酸稳态阻止铁死亡介导MASLD进程
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摘要 Metabolic syndrome-associated steatotic liver disease(MASLD)has become the main driver of liver morbidities,and recently prevalence has risen over 30%.20%-30%of patients develop chronic inflammation and progress to metabolic-associated steatohepatitis(MASH),which is becoming the leading cause of cirrhosis and hepatocellular carcinoma(HCC)[1,2].MASLD is a complex disease where severity is dependent on several factors,including lifestyle,genetics,diet but also iron metabolism.
出处 《Science Bulletin》 2025年第11期1719-1721,共3页 科学通报(英文版)
作者简介 Corresponding author:Luca Valenti,E-mail address:luca.valenti@unimi.it。
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