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新型生物陶瓷材料iRoot SP配合单尖法根管充填治疗对牙体牙髓病患者牙周微生态的影响

Effect of new bioceramic material iRoot SP combined with single cusp root canal fillingon periodontal microecology in patients with dental pulp disease
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摘要 目的 探讨新型生物陶瓷材料iRoot SP配合单尖法根管充填治疗牙体牙髓病的疗效。方法 选取2023年12月—2024年6月诸暨市人民医院收治的112例牙体牙髓病患者,采用随机数表法分成对照组(56例)与观察组(56例),对照组采用新型生物陶瓷材料iRoot SP配合冷侧压法治疗,观察组采用新型生物陶瓷材料iRoot SP配合单尖法根管充填治疗。比较2组患者牙周微生态、龈沟液炎症指标、炎性因子水平、咀嚼效率、疼痛程度(VAS评分)、充填情况及临床疗效。结果 治疗后,2组患者牙周探诊深度(PD)、探诊出血指数(PBI)、牙齿松动度(TM)、菌斑指数(PI)均降低,且观察组均低于对照组(P<0.05);2组基质金属蛋白酶(MMP)-2、MMP-8均降低,且观察组均低于对照组(P<0.05);2组超敏C反应蛋白(hs-CRP)、TNF-α、IL-1β均降低,且观察组均低于对照组(P<0.05)。治疗后,2组患者咀嚼效率均提高,VAS评分均降低,且观察组均优于对照组(P<0.05)。观察组恰填率为89.29%(50/56),高于对照组[73.21%(41/56),P<0.05]。观察组总有效率为96.43%(54/56),高于对照组[83.93%(47/56),P<0.05]。结论 新型生物陶瓷材料iRoot SP配合单尖法根管充填治疗牙体牙髓病效果较好,可改善患者的牙周微生态水平,减轻炎症与疼痛程度,提高咀嚼效率与充填效果。 Objective The present study investigates the efficacy of a newly developed bioceramic material,iRoot SP,in combination with single-pointed root canal fillings.Methods In this study,112 patients diagnosed with dental pulp disease were selected from Zhuji People's Hospital,and the study period spanned from December 2023 to June 2024.The subjects were randomly divided into a control group(n=56)and an observation group(n=56)using a random number table method.The control group were treated with a new bioceramic material known as iRoot SP,in combination with cold manometry.In the observation group,patients were treated with the same bioceramic material,iRoot SP,in combination with a single cusp root canal filling.Periodontal microecology,gingival crevicular fluid inflammatory indicators,inflammatory factor levels,along with masticatory efficiency,pain degree as measured by the VAS score,filling condition categorised,and clinical efficacy were compared.Results After treatment,the probing depth(PD),probing bleeding index(PBI),tooth mobility(TM),plaque index(PI)of the two groups were decreased,and the observation group was lower than those of the control group(P<0.05).The matrix metalloproteinase(MMP)-2 and MMP-8 levels of the two groups following treatment were reduced,and the the observation group was lower than those of the control group(P<0.05).The levels of the hypersensitive C-reactive protein(hs-CRP),TNF-αand IL-1βin both groups decreased following treatment,and the levels of these markers in the observation group was lower than those in the control group(P<0.05).Following the treatment,there was a marked enhancement in masticatory efficiency between the two groups,and the VAS score exhibited a significant decrease was decreased.The observation group was better than those of the control group(P<0.05).The filling rate of the observation group was 89.29%(50/56),which was higher than 73.21%(41/56)of the control group(P<0.05).The total effective rate of the observation group was 96.43%(54/56),which was higher than 83.93%(47/56)of the control group(P<0.05).Conclusion The present study investigates the efficacy of the novel bioceramic material iRoot SP in combination with single-cusp root canal filling as a treatment modality for dental endodontic disease.The findings demonstrate that this approach leads to a favourable improvement in the periodontal microecological level of patients,a reduction in the degree of inflammation and pain,and an enhancement in mastication efficiency and filling efficacy.These observations underscore the merits of adopting this treatment method.
作者 裘卫 胡杨涛 宣桂红 QIU Wei;HU Yangtao;XUAN Guihong(Department of Stomatology,Zhuji People's Hospital,Zhuji,Zhejiang 311800,China;不详)
出处 《中华全科医学》 2025年第6期958-962,共5页 Chinese Journal of General Practice
基金 浙江省医药卫生科技计划项目(2022KY403)。
关键词 新型生物陶瓷材料iRoot SP 单尖法 根管充填治疗 牙体牙髓病患者 牙周微生态 iRoot SP,a new bioceramic material Single point method Root canal filling therapy Patients with dental pulp disease Periodontal microecology
作者简介 通信作者:宣桂红,E-mail:bessxgh@163.com。
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