摘要
目的探讨2型糖尿病合并冠心病患者预后不良的危险因素。方法回顾性分析117例2型糖尿病合并冠心病患者的临床资料,根据临床预后的不同分为预后不良组(67例)和预后良好组(50例)。收集并比较两组患者的基线资料、冠状动脉病变支数、实验室检查指标等,采用二元Logistic回归分析探究影响预后的危险因素。结果预后不良组患者的糖化血红蛋白(HbA1c)水平、冠状动脉多支血管病变占比及合并高血压、高脂血症者占比均显著高于预后良好组(均P<0.01)。Logistic回归分析结果显示,HbA1c、多支血管病变、高血压及高脂血症是这类患者预后不良的独立危险因素(均P<0.05)。结论积极控制血糖、血压及血脂水平,优化冠状动脉血运重建策略,对改善2型糖尿病合并冠心病患者的预后具有重要意义。
Objective To explore the risk factors for poor prognosis in patients with type 2 diabetes mellitus(T2DM)complicated by coronary heart disease(CHD).Methods A retrospective analysis was conducted on the clinical data of 117 patients with T2DM complicating CHD.The patients were divided into a poor prognosis group(67 cases)and a good prognosis group(50 cases)based on their clinical outcomes.Baseline data,number of diseased coronary arteries,laboratory test indicators and other data were collected,and compared between the two groups.Binary Logistic regression analysis was used to identify the risk factors for poor prognosis.Results The levels of glycated hemoglobin(HbA1c),the proportion of patients with multi-vessel coronary artery disease,as well as the prevalence of hypertension and hyperlipidemia were all significantly higher in the poor prognosis group than those in the good prognosis group(all P<0.01).Logistic regression analysis showed that HbA1c,multi-vessel disease,hypertension,and hyperlipidemia were independent risk factors for poor prognosis in patients with T2DM and CHD(all P<0.05).Conclusion Actively controlling blood glucose,blood pressure and lipid levels,as well as optimizing coronary artery revascularization strategies are of significant importance for improving the prognosis of patients with T2DM and CHD.
作者
欧昌元
李衢胜
OU Changyuan;LI Qusheng(Department of Cardiology,Changning People's Hospital,Hengyang Hunan 421500,China)
出处
《实用心电与临床诊疗》
2025年第3期353-357,共5页
PRACTICAL ELECTROCARDIOLOGY AND CLINICAL TREATMENT
关键词
2型糖尿病
冠心病
预后不良
危险因素
type 2 diabetes mellitus
coronary heart disease
poor prognosis
risk factor
作者简介
欧昌元,主要从事冠心病介入诊疗,E-mail:18627471974@163.com。
