摘要
目的:探讨Tubridge与Pipeline血流导向装置对复杂颅内动脉瘤的临床疗效。方法:选取31例接受Pipeline血流导向装置的复杂颅内动脉瘤患者为对照组;同期29例接受Tubridge血流导向装置的复杂颅内动脉瘤患者为观察组。比较两组患者术后6个月随访临床疗效、临床症状缓解情况、动脉瘤闭塞情况(OKM分级);术前及术后6个月脑损伤标志物[血清中枢神经特异蛋白(S100B)、神经元特异性烯醇化酶(NSE)]水平;记录并比较并发症发生情况。结果:两组患者临床有效率、临床症状总缓解率、动脉瘤总闭塞率、脑损伤标志物水平比较,差异无统计学意义(P>0.05)。观察组患者并发症总发生率低于对照组(P<0.05)。结论:Tubridge与Pipeline血流导向装置均可有效减轻复杂颅内动脉瘤患者临床症状,促进颅内动脉瘤闭塞,但Tubridge血流导向装置更能降低患者术后并发症发生风险。
Objective:To investigate the clinical efficacy of Tubridge and Pipeline flow diverting devices in treating complex intracranial aneurysms.Methods:The clinical data of 31 patients with complex intracranial aneurysms who received Pipeline flow diverting device were retrospectively analyzed,and the patients were enrolled as control group.The clinical data of 29 patients who adopted Tubridge flow diverting device during the same period were selected as observation group.According to the follow-up results at 6 months after surgery,the clinical efficacy,clinical symptom relief and aneurysm occlusion(OKM classification)were evaluated.The levels of brain injury markers[serum central nerve specific protein(S100B),neuron-specific enolase(NSE)]before surgery and at 6 months after surgery,and complications were compared between the two groups.Results:There were no significant differences in clinical effective rate,total relief rate of clinical symptoms,total occlusion rate of aneurysms and levels of brain injury markers between the two groups(P>0.05).The total incidence rate of complications in observation group was lower than that in control group(P<0.05).Conclusion:The above two devices for patients with complex intracranial aneurysms can effectively relieve the clinical symptoms and accelerate the occlusion of intracranial aneurysms,but Tubridge flow diverting device can better reduce the risk of postoperative complications.
作者
杨震
宋景军
杨伟
行治国
YANG Zhen;SONG Jing-jun;YANG Wei;XING Zhi-guo(Department of Neurosurgery,Weinan Central Hospital,Weinan 714000,Shaanxi,China)
出处
《川北医学院学报》
2025年第5期577-580,共4页
Journal of North Sichuan Medical College
基金
陕西省重点研发计划项目(S2021-YF-YBSF-0491)。
作者简介
杨震(1983-),男,硕士,副主任医师。E-mail:wnszxyyyangzhen@163.com;通讯作者:行治国。E-mail:shxxing526@163.com。
