摘要
目的探讨血清抗苗勒管激素(AMH)、孕酮联合子宫内膜异位症(EMT)生育指数(EFI)评分对EMT不孕患者腹腔镜术后妊娠的预测价值。方法选取103例EMT不孕患者,根据术后1年妊娠情况分为妊娠组(n=62)和非妊娠组(n=41),另设正常对照组(n=50)。采用化学发光法检测血清AMH和孕酮水平,术中记录EFI评分。比较3组AMH、孕酮及EFI,分析术后妊娠的影响因素及AMH、孕酮及EFI预测价值。结果妊娠组r-AFS分期Ⅰ-Ⅱ期比例高于非妊娠组(P<0.05)。妊娠组AMH、孕酮水平和EFI评分均高于非妊娠组(P<0.05)。Logistic回归分析显示AMH、孕酮水平和EFI评分均为术后自然妊娠的独立影响因素(P<0.05)。ROC曲线分析显示三者联合预测价值最高(AUC=0.972)。结论AMH、孕酮水平联合EFI评分对EMT不孕患者腹腔镜术后妊娠具有良好预测价值,可为临床决策提供参考。
Aim To evaluate predictive value of serum AMH and progesterone combined with EFI score for postoperative pregnancy in infertile EMT patients after laparoscopic surgery.Methods A total of 103 infertile patients with EMT were divided into a pregnancy group(n=62)and a non-pregnancy group(n=41)based on postoperative pregnancy status within 1 year,with 50 healthy volunteers as normal control group.Serum AMH and progesterone levels were measured by chemiluminescence immunoassay,and EFI score was recorded during surgery.Results The proportion of r-AFS stageⅠ-Ⅱwas significantly higher in the pregnancy group(P<0.05).AMH,progesterone levels and EFI score were significantly higher in pregnancy group(P<0.05).Logistic regression analysis showed that AMH,progesterone and EFI score were independent influencing factors for natural pregnancy(P<0.05).ROC curve analysis demonstrated the highest predictive value when combining three indicators(AUC=0.972).Conclusion The combination of AMH,progesterone and EFI score shows good predictive value for postoperative pregnancy after laparoscopic surgery in infertile patients with EMT.
作者
向敏
刘芳
徐培培
王丹
XIANG Min;LIU Fang;XU Peipei;WANG Dan(Department of Gynecology and Obstetrics,Sichuan Provincial Corps Hospital of Chinese People's Armed Police Force,Leshan 614000,Sichuan,China;Department of Gynecology and Obstetrics,Mianyang Central Hospital,Mianyang 621000,Sichuan,China)
出处
《中南医学科学杂志》
2025年第3期492-495,共4页
Medical Science Journal of Central South China
基金
绵阳市卫生健康委科研课题(202020)。
作者简介
向敏,硕士,主治医师,研究方向为妇科内分泌疾病的诊治,E-mail为drxiangmin@163.com;通信作者:刘芳,主治医师,研究方向为妇科微创手术,E-mail为857276528@qq.com。
