摘要
甲状腺癌是一种常见的内分泌系统恶性肿瘤,其发病率全球范围内呈上升趋势。我国发病率更是显著增高。而碘是甲状腺激素的重要成分,对于甲状腺功能和代谢调节至关重要。碘与甲状腺癌患病风险之间的关系备受关注。本综述旨在总结已有文献,分析碘营养水平的评价方法,碘营养水平对甲状腺癌发生发展的影响,碘含量水平失衡与甲状腺癌相关研究存在的偏差分析,进而探讨碘含量异常引起甲状腺癌的可能机制以及分析相关的流行病学研究成果。探讨碘营养水平作为甲状腺癌常规监测指标,并为制定相应策略提供依据。通过现已有研究成果得出结论,甲状腺癌的致病原因复杂,受多种因素影响,而碘营养水平与甲状腺癌发生发展的关系尚未明确。期待更多研究揭示甲状腺癌的发病机制。
Thyroid cancer is a common malignant tumor of the endocrine system,and its incidence is increasing globally.Especially in China,the incidence rate has significantly increased.Iodine,as an important component of thyroid hormones,is crucial for both thyroid function and metabolic regulation.The relationship between iodine and the risk of thyroid cancer has attracted much attention.This review aims to analyze the evaluation methods of iodine nutrition level and its impact on the occurrence and development of thyroid cancer based on existing literature.Through the deviation analysis of the correlation between iodine imbalance and thyroid cancer,the possible mechanism of thyroid cancer caused by abnormal iodine level is explored and the related epidemiological research results are analyzed.The iodine nutrition level is as a routine monitoring indicator for thyroid cancer for providing a basis for developing corresponding strategies.The conclusion drawn from existing research results is that the pathogenesis of thyroid cancer is complex,influenced by multiple factors,and the relationship between iodine nutrition levels and the occurrence and development of thyroid cancer has not been determined.More research is expected to reveal the pathogenic mechanism of thyroid cancer.
作者
霍恺
鲁文慧
高哲敏
张春和
左瑞菊
王澎
HUO Kai;LU Wenhui;GAO Zhemin(Clinical Laboratory Center,Tumor Branch of Cangzhou Medical College,Cangzhou People’s Hospital,Hebei,Cangzhou 061000,China;不详)
出处
《河北医药》
2024年第22期3481-3485,共5页
Hebei Medical Journal
关键词
甲状腺癌
碘营养水平
研究进展
thyroid cancer
iodine nutrition level
research progress
