摘要
目的探讨恶性肿瘤患者发生脑梗死的情况及相关影响因素。方法选择泰安市肿瘤防治院2021年12月—2023年12月恶性肿瘤患者80例,调查患者发生脑梗死的情况分为脑梗死组(n=19)与无脑梗死组(n=61)。比较2组的基本资料,分析恶性肿瘤患者发生脑梗死的相关影响因素。结果80例恶性肿瘤患者,19例发生脑梗死,发生率为23.75%(19/80)。脑梗死组糖类抗原(cancer antigen,CA)125为(17.41±2.25)U/m L,CA199为(32.12±4.19)U/m L,癌胚抗原为(4.39±0.78)ng/mL,白细胞计数为(7.47±1.44)×10^(6)/L,血小板为(244.54±28.53)×10^(9)/L,D-二聚体水平为(493.24±60.87)μg/L,高于无脑梗死组的(12.25±1.92)U/mL、(26.39±3.75)U/mL、(2.52±0.42)ng/mL、(5.49±1.37)×10^(6)/L、(164.16±21.07)×10^(9)/L、(323.18±41.92)μg/L,差异均有统计学意义(P<0.05)。logistic回归分析显示,CA125、CA199、癌胚抗原、白细胞计数、血小板、D-二聚体是恶性肿瘤患者发生脑梗死的相关影响因素(P<0.05)。结论恶性肿瘤患者发生脑梗死的风险较高,CA125、CA199、癌胚抗原、白细胞计数、血小板、D-二聚体是其相关影响因素。
Objective To explore the occurrence of cerebral infarction in patients with malignant tumors and analyze the related influencing factors.Methods A total of 80 patients with malignant tumors from December 2021 to December 2023 at Tai′an Tumour Prevention and Treatment Hospital were selected to investigate the occurrence of cerebral infarction.The patients were divided into a cerebral infarction group of 19 cases and a non cerebral infarction group of 61 cases.The basic data of the two groups were compared to analyze the relevant influencing factors of cerebral infarction in patients with malignant tumors.Results Out of 80 patients with malignant tumors,19 experienced cerebral infarction,with an incidence rate of 23.75%(19/80).The carbohydrate antigen(CA)125 was(17.41±2.25)U/mL,CA199 was(32.12±4.19)U/mL,carcinoembryonic antigen was(4.39±0.78)ng/mL,white blood cell count was(7.47±1.44)×10^(6)/L,platelet count was(244.54±28.53)×10^(9)/L,and D-dimer level was(493.24±60.87)μg/L in the cerebral infarction group,which were higher than those in the non cerebral infarction group(12.25±1.92)U/mL,(26.39±3.75)U/mL,(2.52±0.42)ng/mL,(5.49±1.37)×10^(6)/L,(164.16±21.07)×10^(9)/L,(323.18±41.92)μg/L,the differences were statistically significant(P<0.05).Logistic regression analysis showed that,CA125、CA199、Carcinoembryonic antigen,white blood cell count,platelets and D-dimer are related influencing factors for cerebral infarction in patients with malignant tumors(P<0.05).Conclusion Patients with malignant tumors have a higher risk of developing cerebral infarction,CA125,CA199,carcinoembryonic antigen,white blood cell count,platelets,and D-dimer are related influencing factors.
作者
黄丽
范亚男
唐琴
周国庆
崔健
HUANG Li;FAN Yanan;TANG Qin;ZHOU Guoqing;CUI Jian(Department of Internal Medicine,Tai′an Tumour Prevention and Treatment Hospital,Tai′an Shandong 271000,China;Department of Internal Medicine,Tai′an Central Hospital Affiliated to Qingdao University,Tai′an Shandong 271000,China;Department of Internal Medicine,the Second Affiliated Hospital of Shandong First Medical University,Tai′an Shandong 271000,China)
出处
《中国卫生标准管理》
2025年第2期102-105,共4页
China Health Standard Management
关键词
恶性肿瘤
脑梗死
影响因素
癌胚抗原
白细胞计数
血小板
malignant tumors
cerebral infarction
influencing factors
carcinoembryonic antigen
white blood cell count
platelet
作者简介
通信作者:崔健。
