摘要
晚睡甚至通宵不睡等易引起昼夜节律紊乱,扰乱体内生物钟的表达,导致骨骼肌萎缩、线粒体功能障碍等健康问题。通过梳理国内外关于骨骼肌昼夜节律的研究,发现:1)骨骼肌核心生物钟通过调控时钟控制基因、骨骼肌调节因子以及线粒体呼吸从而影响骨骼肌质量、结构功能以及线粒体功能。2)骨骼肌会因运动等外部信号改变生物钟基因振荡,重新调整骨骼肌昼夜节律,促进健康。3)在上午进行锻炼,主要改善睡眠健康和肌生成;在下午/傍晚进行锻炼,主要改善代谢健康并且有利于运动表现。4)在微重力环境下,运动可能通过调节生物钟基因表达改善睡眠不足与昼夜节律紊乱。
Sleeping late or even staying up all night can easily cause circadian rhythm disorders,disrupting the expression of the body's biological clock and leading to health problems such as skeletal muscle atrophy and mitochondrial dysfunction.By combing domestic and international studies on skeletal muscle circadian rhythms,results show that:1)The skeletal muscle core biological clock influences skeletal muscle mass,structural function,and mitochondrial function through the regulation of clock-controlled genes,skeletal muscle regulatory factors,and mitochondrial respiration.2)Skeletal muscle alters biological clock gene oscillations in response to external signals such as exercise,readjusting skeletal muscle circadian rhythms and promoting health.3)Exercise in the morning improves sleep health and myogenesis;exercising in the afternoon/evening improves metabolic health and facilitates athletic performance.4)In microgravity,exercise may ameliorate sleep lack and circadian rhythm disruption by regulating biological clock gene expression.
作者
唐朝
汪毅
TANG Chao;WANG Yi(Renmin University of China,Beijing 100872,China.)
出处
《中国体育科技》
北大核心
2025年第2期63-72,共10页
China Sport Science and Technology
基金
国家社会科学基金一般项目(20BTY029)。
关键词
运动
骨骼肌
生物钟基因
昼夜节律
运动健康促进
微重力
exercise
skeletal muscle
biological clock gene
circadian rhythm
exercise health promotion
microgravity
作者简介
第一作者:唐朝(1999-),男,硕士,主要研究方向为运动与昼夜节律,E-mail:tangchao303@163.com;通信作者:汪毅(1980-),男,副教授,博士,博士研究生导师,主要研究方向为宇航员运动防护理论与实践,E-mail:Wang-yi@ruc.edu.cn。
