摘要
目的:分析急性心肌梗死(AMI)患者行经皮冠状动脉介入治疗(PCI)术后心力衰竭(HF)发生的影响因素。方法:回顾性分析2020年1月-2021年1月郑州人民医院收治的98例行PCI的AMI患者临床资料。统计患者术后HF发生情况,另收集患者的年龄、性别等资料,探究此类患者术后发生HF的影响因素。结果:98例行PCI术的AMI患者中,发生HF的共有14例(14.29%)。单因素分析结果显示:年龄、糖尿病史、是否合并室性心律失常、术后TIMI心肌灌注分级、TNF-α水平、Hcy水平与AMI患者PCI后并发HF有关,差异均有统计学意义(χ^(2)=7.881、9.638、5.347、6.822;t=22.024、22.883,P<0.05);logistic回归分析结果显示:年龄>60岁、有糖尿病史、合并室性心律失常、术后心肌梗死溶栓治疗(TIMI)心肌灌注分级0~1级、肿瘤坏死因子-α (TNF-α)水平高、同型半胱氨酸(Hcy)水平高为AMI患者PCI后并发HF的独立危险因素(OR=5.278、6.954、4.500、4.741、7.025、7.635,P<0.05)。结论:年龄>60岁、合并室性心律失常、有糖尿病史、术后TIMI心肌灌注分级0-1级、TNF-α水平高、Hcy水平高为AMI患者PCI后并发HF的独立危险因素。
Objective:To analyze the related factors of heart failure(HF)after percutaneous coronary intervention(PCI)in patients with acute myocardial infarction(AMI).Methods:A retrospective analysis was conducted on the clinical data of 98 AMI patients who underwent PCI admitted to Zhengzhou People’s Hospital from January 2020 to January 2021,and the incidence of postoperative HF was recorded.Age,gender and other data of patients were collected to explore the relevant factors for postoperative HF in such patients.Results:Among 98 AMI patients who underwent PCI,a total of 14 cases developed HF,with an incidence rate of 14.29%.Univariate analysis showed that age,ventricular arrhythmia,history of diabetes,myocardial perfusion grade after thrombolytic therapy for postoperative myocardial infarction(TIMI),tumor necrosis factor-α(TNF-α),levels of homocysteine(Hcy)and homocysteine(Hcy)were related to the occurrence of HF in AMI patients after PCI(χ^(2)=7.881,9.638,5.347,6.822;t=22.024,22.883;P<0.05).Logistic regression analysis showed that age>60 years old,with ventricular arrhythmia,history of diabetes,TIMI myocardial perfusion grade 0~1,TNF-α,high levels of Hcy and high levels of Hcy are independent risk factors for postoperative HF in AMI patients after PCI(OR=5.278,6.954,4.500,4.741,7.025,7.635;P<0.05).Conclusion:Age>60,with ventricular arrhythmia,history of diabetes,TIMI myocardial perfusion grade 0-1,TNF-α,high levels of Hcy and high levels of Hcy are independent risk factors for concurrent HF in AMI patients after PCI.
作者
逯平
马莉红
王玲玲
Lu Ping;Ma Lihong;Wang Lingling(Cardiovascular Department,Zhengzhou People’s Hospital,Zhengzhou,Henan,450000,China)
出处
《黑龙江医学》
2025年第4期404-406,共3页
Heilongjiang Medical Journal
关键词
急性心肌梗死
经皮冠状动脉介入治疗
心力衰竭
Acute myocardial infarction
Percutaneous coronary intervention
Heart failure
