摘要
肺癌骨转移在晚期肺癌患者中较为常见,其治疗研究取得了显著进展。全身治疗方面,化疗是传统的治疗方案;靶向治疗针对特定基因突变的肺癌患者展现出强大的疗效;免疫治疗可通过激活机体免疫系统,为肺癌骨转移患者带来新的治疗选择,可单独应用或与其他疗法联合。抗骨转移药物如双膦酸盐和地舒单抗在减少骨破坏及骨相关不良事件方面发挥重要作用。局部治疗方面,放疗可精准照射肿瘤病灶,缓解疼痛症状;手术治疗适用于特定的骨转移病灶,恢复骨骼稳定性和功能。此外,镇痛治疗和心理干预可缓解患者的疼痛和焦虑。这些治疗研究进展为肺癌骨转移患者带来新的希望。
Bone metastasis of lung cancer is relatively common in patients with advanced lung cancer,the treatment research of which has been made remarkable progress.In terms of systemic therapy,chemotherapy is the traditional treatment plan;targeted therapy shows strong efficacy in treating lung cancer patients with specific gene mutations;immunotherapy can bring new treatment options for lung cancer patients with bone metastasis by activating the body's immune system,which can be used alone or in combination with other therapies.Anti bone metastasis drugs such as bisphosphonates and denosumab play an important role in reducing bone destruction and bone-related adverse events.In terms of local therapy,radiotherapy can accurately irradiate tumor lesions and relieve pain symptoms;surgical treatment is suitable for specific bone metastasis to restore bone stability and function.In addition,analgesic treatment and psychological intervention can alleviate patients'pain and anxiety.These therapeutic advances bring new hope to patients with lung cancer bone metastasis.
作者
于德刚
贾军梅
Yu Degang;Jia Junmei(First Medical College,Shanxi Medical University,Taiyuan 030001,China;Department of Respiratory Oncology,First Hospital of Shanxi Medical University,Taiyuan 030001,China)
出处
《国际肿瘤学杂志》
2024年第12期789-793,共5页
Journal of International Oncology
关键词
肺肿瘤
肿瘤转移
治疗
Lung neoplasms
Neoplasm metastasis
Therapy
作者简介
通信作者:贾军梅,Email:jiajunmei1972@163.com。
