摘要
硒是人体必需的微量营养元素之一,对人体的生命活动非常重要。旨在为富硒生物活性肽的研究和应用提供理论依据,总结了富硒生物活性肽的原料来源、制备方法、生物活性,并对硒与肽的结合方式以及富硒生物活性肽的构效关系等研究进展进行了阐述。富硒生物活性肽的原料主要来源于生物载体转化,主要有植物来源、动物来源及微生物来源;通过酶解法、微生物发酵法等可制备富硒生物活性肽,其具有抗氧化、抗疲劳、降血压、抗炎等多种生物活性;富硒生物活性肽的生物活性是硒、肽共同作用的结果,与氨基酸的排列序列、空间结构、相互作用力等有密切的联系,其构效关系有待进一步研究。
Selenium is an essential trace nutritional element that is very important for human life activities. Aiming to provide a theoretical basis for the research and application of selenium-enriched bioactive peptides, the raw material sources, preparation methods, bioactivities of selenium-enriched bioactive peptides were summarized. The research progress on selenium and peptides binding modes as well as the structure-activity relationship of selenium-enriched bioactive peptides were elaborated. The raw materials of selenium-enriched bioactive peptides mainly come from the transformation of biocarriers, such as plant sources, animal sources, and microbial sources.The selenium-enriched bioactive peptides can be prepared by enzymatic hydrolysis and microbial fermentation methods, which have a wide range of bioactivities, such as antioxidant, anti-fatigue, blood pressure lowering, anti-inflammatory, and so on. The bioactivities of selenium-enriched bioactive peptides are the results of the joint action of selenium and peptides, which are closely related to the sequence, spatial structure and interaction force of amino acids, but their structure-activity relationships need to be further studied.
作者
侯春艳
杨趁仙
HOU Chunyan;YANG Chenxian(College of Food Science and Engineering,Henan University of Technology,Zhengzhou 450001,China)
出处
《中国油脂》
北大核心
2025年第1期115-121,共7页
China Oils and Fats
基金
河南省科技研发计划联合基金(应用攻关类)(232103810064)
河南省重点研发专项(231111111800)
国家自然科学基金(32202079)
国家自然科学基金(联合基金)重点项目(U21A20270)
河南省重点研发与推广专项(科技攻关)(222102110112)
河南工业大学创新基金支持计划专项资助(2021ZKCJ03)
河南工业大学青年骨干教师培育计划(21421237)。
关键词
富硒
生物活性肽
制备方法
生物活性
构效关系
selenium-enrichment
bioactive peptides
preparation method
bioactivity
structure-activity relationship
作者简介
侯春艳(2003),女,在读本科,食品科学与工程专业(E-mail)3420400660@qq.com;通信作者:杨趁仙,硕士生导师,博士(E-mail)ycxyou@163.com。
