摘要
目的探讨半夏白术天麻汤治疗2型糖尿病合并颈动脉粥样硬化的临床疗效。方法98例2型糖尿病合并颈动脉粥样硬化患者按数字表法随机分为半夏白术天麻汤组及常规治疗组各49例,常规治疗组患者进行常规治疗,半夏白术天麻汤组患者在常规治疗基础上给予半夏白术天麻汤治疗。6个月为1疗程。结果治疗1疗程后,半夏白术天麻汤组患者空腹血糖、餐后2h血糖及糖化血红蛋白水平均低于常规治疗组;总胆固醇、甘油三酯及低密度脂蛋白胆固醇水平低于常规治疗组,高密度脂蛋白胆固醇水平高于常规治疗组;颈动脉内膜中层厚度、斑块体积及斑块数量均低于常规治疗组。不良反应发生率组间比较差异无统计学意义。结论在常规治疗基础上合用半夏白术天麻汤治疗2型糖尿病合并颈动脉粥样硬化可有效降低患者血糖、血脂水平,改善颈动脉斑块状况,且不明显增加不良反应。
Objective To explore the therapeutic efficacy of Banxia Baizhu Tianma decoction in managing type 2 diabetes mellitus coupled with carotid atherosclerosis.Methods A total of 98 patients with type 2 diabetes mellitus and carotid atherosclerosis were randomly and equally allocated into two groups:the Banxia Baizhu Tianma decoction group and the conventional treatment group.The conventional treatment group received standard medical therapy,whereas the Banxia Baizhu Tianma decoction group was administered Banxia Baizhu Tianma decoction alongside the conventional treatment.Six months are one course of treatment.Results Upon completion of the treatment regimen,patients in the Banxia Baizhu Tianma decoction group demonstrated significantly lower fasting blood glucose,2-hour postprandial blood glucose,and glycated hemoglobin levels in comparison with the conventional treatment group.Additionally,the levels of total cholesterol,triglyceride,and low-density lipoprotein were notably reduced in the Banxia Baizhu Tianma decoction group,while high-density lipoprotein levels were enhanced.The Banxia Baizhu Tianma decoction group exhibited diminished intima-media thickness,plaque volume,and plaque count in the carotid arteries relative to the conventional treatment group.No statistically significant disparity in the incidence of adverse reactions was observed between the two groups.Conclusion The integration of Banxia Baizhu Tianma decoction in the therapeutic regimen for patients afflicted with type 2 diabetes mellitus and carotid atherosclerosis substantively reduces blood glucose and lipid levels,ameliorates carotid plaque condition,and there is no significant increase in adverse reactions.
作者
孙小明
翟江
杨庆华
赵贞
SUN Xiao-ming;ZHAI Jiang;YANG Qing-hua;ZHAO Zhen(Department of Function,The Second Affiliated Hospital of Hebei North University,Zhangjiakou,Hebei 075100,China;Department of Ultrasound,Hebei Huaao Hospital,Zhangjiakou,Hebei 075000,China)
出处
《河北北方学院学报(自然科学版)》
2025年第2期23-27,共5页
Journal of Hebei North University:Natural Science Edition
基金
2023年张家口市市级科技计划项目(No.2322167D)。
关键词
半夏白术天麻汤
2型糖尿病
颈动脉粥样硬化
血糖
血脂
颈动脉斑块
Banxia Baizhu Tianma decoction
Type 2 diabetes
Carotid atherosclerosis
Blood glucose
Blood lipid
Carotid plaque
作者简介
孙小明(1981-),女,河北张家口人,医师,研究方向:超声医学。
