摘要
目的 :研究下肢骨折后血液流变学的变化及伤科接骨片对血液流变特性的影响。方法 :2 5例下肢骨折患者 ,给予伤科接骨片每次 4片 ,po ,tid ,于未用药前及服药 7d后进行血液流变学检测 ,并与 2 5例正常人血液流变学指标进行比较。结果 :2 5例下肢骨折患者用药后凝血因子Ⅰ、血细胞比容、红细胞聚集指数、全血还原粘度明显下降 ,红细胞变形指数则显著升高 ,与用药前比较差异有显著性 (P <0 .0 5或P <0 .0 1) ,与正常组相比差异无显著性 (P >0 .0 5 )。结论 :伤科接骨片能有效改善血液流变学特性 ,促进骨折愈合 ,预防下肢深静脉血栓形成。
Objective:To study the hemorheological changes in patients with lower limb fracture and the influence of shangke bone knitting tablets on hemorrhemorrheology. Methods:25 patients with lower limb fracture were given each 4 shangke bone knitting tablets p.o., t.i.d.. Hemorheological parameters of the patients before the medication and seven days after the termination of treatment were compared with one another and with those of 25 normal people serving as controls. Results:7 days after the termination of treatment, there was a striking decrease in fibrinogen, hematocrit, whole blood reduced viscosity, erythrocyte aggregation index and erythrocyte sedimentation rate. In contrast, the erythocyte deformability index was evidently increased. The differences were significant ( P <0.05) or highly significant ( P <0.01) when these parameters were compared with those of the patients before the medication. The differences, however, were insignificant when the parameters of the patients after the treatment were compared with those of the normal controls ( P >0.05). Conclusion: Shangke bone knitting tablets were shown to be capable of obviously improving the hemorheological status, promoting bony union and preventing lower limb deep venous thrombosis in patients with lower limb fracture.
出处
《医药导报》
CAS
2002年第12期773-774,共2页
Herald of Medicine
