摘要
针灸作为一种传统中医治疗手段,已广泛应用于临床治疗以及预防缺血性中风(ischemic stroke,IS),并得到医者及患者的广泛认可,但其中枢效应机制仍未明确。近几年,在多学科交叉的背景下,如何判定针刺治疗IS疗效、证实其作用机制、如何客观量化与标准化其治疗过程是目前此治疗领域研究的研究重点和热点。功能磁共振成像(functional magnetic resonance imaging,fMRI)技术是一种能客观显示脑部微观形态结构以及其功能变化,并能反映针刺治疗IS与中枢系统之间联系作用的现代影像技术,其为推动针刺治疗IS现代化提供客观详实的依据,为探索针刺治疗IS及其后遗症方法的研究进展作出了巨大贡献。本文通过总结fMRI用于研究针刺治疗IS中枢机制的技术原理、反映针刺治疗IS以及IS后遗症的中枢机制3个方面,介绍近年fMRI技术诠释针刺治疗IS的发展现状及面临问题,探索出基于fMRI技术以提高针刺治疗IS疗效的新方法及新方向,便于为临床提供更加精准有效的治疗方案,望进一步减轻IS患者及家庭的心理及经济负担。
As a traditional Chinese medicine treatment,acupuncture has been widely used in clinical treatment and prevention of ischemic stroke(IS).It has been widely recognized by doctors and patients,but its central effect mechanism is still unclear.In recent years,under the background of multidisciplinary cross,how to determine the efficacy of acupuncture in the treatment of IS,confirm its mechanism of action,and how to objectively quantify and standardize the treatment process are the research focus and hotspots in this treatment field.Functional magnetic resonance imaging(fMRI)is a modern imaging technology that can objectively show the micro-morphological structure of the brain and its functional changes,and can reflect the relationship between acupuncture treatment of IS and the central system.It provides an objective and detailed basis for promoting the modernization of acupuncture treatment of IS,and has made great contributions to the research progress of acupuncture treatment of IS and its sequelae.By summarizing the technical principle of fMRI used to study the central mechanism of acupuncture in the treatment of IS,reflecting the central mechanism of acupuncture in the treatment of IS and the sequelae of IS,this paper introduces the development status and problems of fMRI technology in the interpretation of acupuncture in the treatment of IS in recent years,and explores the new methods and new directions based on fMRI technology to improve the curative effect of acupuncture in the treatment of IS,so as to provide more accurate and effective treatment plan for the clinic,and hope to further reduce the psychological and economic burden of IS patients and their families.
作者
仲思潼
曹馨元
梁吉
孙忠人
尹洪娜
ZHONG Sitong;CAO Xinyuan;LIANG Ji;SUN Zhongren;YIN Hongna(Graduate School,Heilongjiang University of Chinese Medicine,Harbin 150040,China;Seven Departments of Acupuncture,Second Affiliated Hospital of Heilongjiang University of Chinese Medicine,Harbin 150001,China)
出处
《磁共振成像》
CAS
CSCD
北大核心
2024年第11期174-179,共6页
Chinese Journal of Magnetic Resonance Imaging
基金
国家重点研发计划项目(编号:2022YFC3500403、2022YFC3500405)
黑龙江省中医药科研项目(编号:GY2022-11)。
关键词
功能磁共振成像技术
针刺治疗机制
缺血性中风
脑梗死
磁共振成像
functional magnetic resonance imaging
mechanism of acupuncture treatment
ischemic stroke
cerebral infarction
magnetic resonance imaging
作者简介
通信作者:尹洪娜,E-mail:hljtcmacu@163.com。
