摘要
目的探讨健康体检人群甘油三酯葡萄糖指数(TyG)与脑血流动力学积分值(CVHI)的相关性。方法本研究为横断面研究,选取2020年6月至2021年5月在新疆医科大学第一附属医院健康管理中心体检且符合纳排标准的12785例健康体检人群为研究对象,收集其一般资料、体格检查、生化指标等结果。使用可视化分箱根据TyG<8.379、8.379~8.785、8.785~9.236、≥9.236将研究对象分为Q1组(3196例)、Q2组(3196例)、Q3组(3197例)和Q4组(3196例),比较4组各项数据差异,采用logistic回归分析和Spearman等级相关分析评估健康体检人群TyG与CVHI的相关性。结果CVHI随着TyG增加而逐渐减小,且CVHI异常率随着TyG的升高而逐渐增加(H=451.007,χ^(2)=188.571)(均P<0.001)。Q1、Q2、Q3、Q4组CVHI高危个体检出率分别为15.2%、22.3%、27.2%、35.3%。当TyG≥9.236时,健康体检人群CVHI下降(OR=1.282,95%CI:1.028~1.598),CVHI与TyG呈负相关(rs=-0.200)(均P<0.05)。结论健康体检人群TyG与CVHI之间存在负相关,当TyG≥9.236时,提示脑血流动力学可能存在异常,需要引起重视。
Objective To investigate the correlation between triglyceride glucose index(TyG)and cerebral hemodynamic score values(CVHI)in population receiving physical examination.Methods In this cross-sectional study,12785 people who had medical checkups and received physical examination at the Health Management Center of the First Affiliated Hospital of Xinjiang Medical University from June 2020 to May 2021 and met the criteria for natriuresis were selected as the study subjects.The general information,physical examination results and biochemical indexes were collected in these people.Using the visualization score box,the study subjects were divided into 4 groups according to TyG<8.379,8.379-8.785,8.785-9.236,and≥9.236:Q1 group(3196 cases),Q2 group(3196 cases),Q3 group(3197 cases),and Q4 group(3196 cases).The differences of the indices among the four groups were compared.The logistic regression analysis and Spearman rank correlation analysis were used to assess the correlation between TyG and CVHI in the population undergoing health checkups.Results CVHI decreased gradually with the increase of TyG,and the abnormal rate of CVHI increased gradually with the increase of TyG(H=451.007,χ^(2)=188.571)(both P<0.001).The detection rates of individuals at high risk of CVHI in the Q1,Q2,Q3,and Q4 groups was 15.2%,22.3%,27.2%,and 35.3%,respectively.When TyG≥9.236,CVHI decreased in the population receiving physical examination(OR=1.282,95%CI:1.028-1.598),and CVHI was negatively correlated with TyG(r s=-0.200)(both P<0.05).Conclusion There is a negative correlation between TyG and CVHI in the population receiving physical examination,and when TyG≥9.236,it suggests that cerebral hemodynamics may be abnormal,which warrants attention.
作者
王敏
姚华
刘冬霞
王育珊
Wang Min;Yao Hua;Liu Dongxia;Wang Yushan(Additional Ward,Department of Critical Care Medicine 1,the First Affiliated Hospital of Xinjiang Medical University,Urumqi830011,China;Health Management Center,the First Affiliated Hospital of Xinjiang Medical University,Urumqi830011,China;School of Nursing,Xinjiang Medical University,Urumqi830011,China;Health Management Centre,Xinjiang Uygur Autonomous Region People′s Hospital,Urumqi830001,China)
出处
《中华健康管理学杂志》
CAS
CSCD
北大核心
2024年第12期905-909,共5页
Chinese Journal of Health Management
基金
中华医学会健康管理学分会博士联盟课题(2020BSLM16)。
关键词
体格检查
甘油三酯葡萄糖指数
脑血流动力学
卒中
相关性
Physical examination
Triglyceride glucose index
Cerebral hemodynamics
Stroke
Correlation
作者简介
通信作者:王育珊,Email:34160869@qq.com。
