摘要
目的:探讨使用孟鲁司特钠对轻度持续性支气管哮喘患儿肺功能和睡眠质量的临床效果。方法:选取2021年1月至2023年12月南华大学附属第二医院收治的单独使用孟鲁司特钠治疗的轻度持续性支气管哮喘患儿66例作为研究对象,治疗12周,收集患儿治疗前后的肺功能和睡眠质量等指标。结果:治疗后的患儿日间/夜间症状评分及短效β2-受体激动剂使用量改善明显优于治疗前,差异有统计学意义(P<0.05);治疗前的第1秒用力呼气容积和呼气流量峰值明显低于治疗后,差异有统计学意义(P<0.05);治疗后患儿的儿童支气管哮喘控制测试评分高于治疗前,儿童睡眠紊乱量表显著低于治疗前,差异有统计学意义(P<0.05)。结论:对轻度持续性支气管哮喘患儿单独使用孟鲁司特钠进行治疗,安全性高且有助于改善患儿的哮喘症状、肺功能及睡眠质量,值得临床上推广应用。
Objective:To investigate the clinical effects of montelukast sodium on pulmonary function and sleep quality in children with mild persistent bronchial asthma.Methods:Sixty-six children with mild persistent bronchial asthma treated with Montelukast sodium alone for 12 weeks in our hospital from January 2021 to December 2023 were retrospectively selected for the study.Pulmonary function and sleep quality of the children before and after treatment were collected.Results:After treatment,the improvement of day/night symptom scores and the use of short-actingβ2-receptor agonists was significantly better than that before treatment,with statistical significance(P<0.05),and the peak of forced expiratory volume and expiratory flow in the first second before treatment were significantly lower than that after treatment,with statistical significance(P<0.05).After treatment,the score of children′s bronchial asthma control test after the treatment was higher than that before treatment,and the score of Sleep Disturbance Scale for Children was significantly lower than that before treatment(P<0.05).Conclusion:Montelukast sodium alone in the treatment of children with mild persistent bronchial asthma is safe and helpful to improve the asthma symptoms,pulmonary function and sleep quality of children,and is worthy of clinical application.
作者
傅艳姣
FU Yanjiao(Department of Pediatrics,The Second Affiliated Hospital of University of South China,Hengyang 421001,China)
出处
《世界睡眠医学杂志》
2024年第10期2249-2251,共3页
World Journal of Sleep Medicine
作者简介
傅艳姣(1991.08-),女,本科,住院医师,研究方向:儿科疾病诊疗,E-mail:15973400320@163.com。
