摘要
Pattern recognition receptors(PRRs)are integral to plant immunity,functioning as the first line of defense against pathogens.Among these,receptor kinases(RKs)play a critical role in recognizing external signals and initiating immune responses.Recent studies by Li et al.(2024)have identified the G-type lectin RK ZmLecRK1 in maize as essential for resistance to Pythium aphanidermatum and other fungal pathogens.A key finding is that a resistant variant of ZmLecRK1,which carries an alanine at position 404,has emerged in maize,while the ancestral form,with a serine at this position,is conserved across most grasses.This amino acid substitution significantly influences the interaction with the co-receptor BRASSINOSTEROID INSENSITIVE 1-ASSOCIATED RECEPTOR KINASE 1(BAK1),enhancing immune complex formation and subsequent defense signaling.This work underscores the importance of genetic variation in enhancing disease resistance,offering potential strategies for crop improvement through targeted genetic modification.
基金
PID2021-126006OB-100 and PDC2022-133742-100 from the Spanish Ministry of Science and Innovation.
作者简介
Correspondence:Miguel-Ángel Torres,miguelangel.torres@upm.es;Correspondence:Lucía Jordá,lucia.jorda@upm.es。
