摘要
目的:比较飞秒激光小切口角膜基质透镜取出术(SMILE)与飞秒激光辅助准分子激光原位角膜磨镶术(FS-LASIK)术后角膜上皮厚度(CET)的变化特点。方法:收集2022-12/2023-11在乌鲁木齐爱尔眼科医院接受屈光手术患者187例187眼。按手术方式分为SMILE组110例110眼和FS-LASIK组77例77眼。应用眼前节光学相干断层扫描技术(OCT)分别于术前和术后1 wk,1、3、6 mo测量患者的CET。结果:比较术后6 mo时角膜中央区、旁中央区、中周区角膜上皮厚度变化量(△CET),SMILE的特点为中央区增厚最明显,中周区上皮最少;FS-LASIK的特点为旁中央区增厚最明显,中周区最少。术后1 wk,1、3、6 mo时SMILE与FS-LASIK组角膜0-7 mm范围的平均ΔCET与术前等效球镜均具有相关性。结论:SMILE和FS-LASIK术后6 mo内上皮增厚程度随时间变化有相似的趋势和不同的特点,二者△CET均与术前等效球镜正相关。
·AIM:To compare the changes in corneal epithelial thickness(CET) after small incision lenticule extraction(SMILE) and femtosecond laser-assisted in situ keratomileusis(FS-LASIK).·METHODS:A total of 187 patients(187 eyes) who underwent either SMILE or FS-LASIK at Urumqi Aier Eye Hospital between December 2022 and November 2023 were collected.The patients were divided into SMILE group and FS-LASIK group according to surgical methods.The CET of the patients was measured by optical coherence tomography(OCT) system before surgery and at 1 wk,1,3,and 6 mo postoperatively.·RESULTS:Changes in corneal epithelial thickness(△CET) in the central,paracentral,and mid-peripheral regions were compared at 6 mo postoperatively.The SMILE group was characterized by the most significant thickening in the central area and the least thickening in the mid-peripheral area;while the FS-LASIK group was characterized by the most significant thickening in the paracentral area and the least thickening in the mid-peripheral region.At 1 wk,1,3,and 6 mo postoperatively,within the 0-7 mm corneal area,the △CET for both the SMILE and FS-LASIK groups was correlated with the preoperative spherical equivalent.·CONCLUSION:Within 6 mo postoperatively,both SMILE and FS-LASIK showed a similar trend in epithelial thickening but with distinct characteristics.The change in corneal epithelial thickness for both procedures was positively correlated with the preoperative diopter.
作者
张杨婧
马立威
张帆
柯春梅
王瑞夫
祖丽皮娅
Zhang Yangjing;Ma Liwei;Zhang Fan;Ke Chunmei;Wang Ruifu;Zu Lipye(Aier Eye Medical Center of Anhui Medical University,Hefei 230031,Anhui Province,China;Urumqi Aier Eye Hospital,Urumqi 830000,Xinjiang Uyghur Autonomous Region,China;Shenyang Aier Excellence Eye Hospital,Shenyang 110000,Liaoning Province,China)
出处
《国际眼科杂志》
CAS
2025年第1期37-41,共5页
International Eye Science
基金
乌鲁木齐市卫生健康委科技计划项目支持(No.202370)。
作者简介
张杨婧,女,硕士,主治医师,研究方向:屈光不正与屈光手术;通讯作者:马立威,女,博士,博士研究生导师,主任医师,研究方向:晶状体及视网膜疾病的基础与临床研究.maliwei@aierchina.com。
