摘要
Poly(butylene adipate-co-terephthalate),PBAT,is one of the most popular plastics nowadays and is becoming a large burden to the environment when PBAT waste is accumulated.Biodegradation of PBAT is an environmentally friendly method to treat PBAT waste.In the past two decades,a couple of microbial strains or mixed strains have been chemically characterized.From this,many PBAT depolymerases have been isolated and further structurally determined.The review we focused on the PBAT depolymerases that have been structurally characterized,including lipases,esterases,and cutinases.We also discussed which shape of the substrate-binding tunnels is beneficial for recognizing and decomposing polymer chains of PBAT,which would be important guidance in directing the designation of PBAT depolymerases.
基金
supported by the National Key Research and Devel-opment Program of China(2021YFC2104000)
Hubei Hongshan Laboratory(2022hszd030)
the National Natural Science Foundation of China(32271318).
作者简介
Corresponding author:ReyTing Guo.State Key Laboratory of Biocatalysis and Enzyme Engineering,Hubei Hongshan Laboratory,Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources,Hubei Key Laboratory of Industrial Biotechnology,School of Life Sciences,Hubei University,Wuhan,430062,People's Republic of China.E-mail:guoreyting@hubu.edu.cn Corresponding author:Yu Yang.E-mail addresses:yangyu@hubu.edu.cn,These authors contributed equally;Zhongrui Wang,These authors contributed equally。