阿托伐他汀辅助治疗高血压脑出血患者的效果

Effect of Atorvastatin as an Adjuvant Therapy in Patients with Hypertensive Intracerebral Hemorrhage

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摘要目的分析阿托伐他汀辅助治疗高血压脑出血患者的效果。方法非随机选取2021年2月—2024年2月湄潭县人民医院收治的高血压脑出血患者84例为研究对象。按治疗方法分为阿托伐他汀组与传统组,每组42例。阿托伐他汀组与传统组都给予常规治疗,传统组给予甘露醇结合乙酰谷酰胺治疗,阿托伐他汀组在传统组治疗基础上联合阿托伐他汀治疗。比较两组的总有效率、Barthel指数评分、血脂指标。结果阿托伐他汀组总有效率为97.62%(41/42),高于传统组的73.81%(31/42),差异有统计学意义(χ^(2)=9.722,P<0.05)。治疗后,阿托伐他汀组Barthel指数评分高于传统组,总胆固醇、甘油三酯低于传统组,差异有统计学意义(P均<0.05)。结论高血压脑出血患者采用阿托伐他汀辅助治疗,临床效果明显,可改善患者的日常生活能力,降低患者的总胆固醇、甘油三酯水平。 Objective To analyze the effect of atorvastatin in the adjunctive treatment of patients with hypertensive cerebral hemorrhage.Methods Eighty-four cases of hypertensive cerebral hemorrhage patients admitted to Meitan County People's Hospital from February 2021 to February 2024 were non-randomly selected as the study subjects.They were divided into atorvastatin group and traditional group according to treatment method,with forty-two cases in each group.Atorvastatin group and traditional group were given conventional treatment,traditional group was given mannitol combined with acetylglutamide treatment,and atorvastatin group was treated with atorvastatin in combination with treatment in the conventional group.The total effective rate,Barthel index score,and lipid index of the two groups were compared.Results The total effective rate in the atorvastatin group was 97.62%(41/42),which was higher than 73.81%(31/42)in the traditional group,and the difference was statistically significant(χ^(2)=9.722,P<0.05).After treatment,the Barthel index score of the atorvastatin group was higher than that of the traditional group,and the total cholesterol and triglycerides were lower than those of the traditional group,and the differences were statistically significant(all P<0.05).Conclusion Adjunctive therapy with atorvastatin in patients with hypertensive cerebral hemorrhage is clinically effective in improving patients'ability to perform daily life and lowering their total cholesterol and triglyceride levels.

作者范永智 FAN Yongzhi(Neurosurgery Department,Meitan County People's Hospital,Zunyi 564100,Guizhou,China)

机构地区湄潭县人民医院神经外科

出处《系统医学》 2024年第22期138-140,156,共4页 Systems Medicine

关键词阿托伐他汀高血压脑出血日常生活能力总胆固醇甘油三酯 Atorvastatin Hypertensive intracerebral hemorrhage Daily living ability Total cholesterol Triglyceride

分类号 R743 [医药卫生—神经病学与精神病学]

作者简介范永智(1983-),男,本科,副主任医师,研究方向为神经外科疾病的诊治。