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超声造影联合增强CT对肝局灶性结节与小肝细胞癌早期的临床鉴别诊断价值

Clinical Value of Contrast-enhanced Ultrasound Combined with Enhanced CT in the Early Differential Diagnosis of Focal Liver Nodules and Small Hepatocellular Carcinoma
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摘要 目的分析超声造影联合增强CT对肝局灶性结节与小肝细胞癌早期的临床鉴别诊断价值。方法选取新干县人民医院于2020年1月-2023年8月收治的疑似肝局灶性结节与小肝细胞癌患者60例作为研究对象,按照随机数字表法将所有患者分为对照组和研究组,每组30例。对照组应用增强CT,研究组在对照组基础上应用肝脏超声造影。比较两组患者不同阶段(动脉期、门脉期、延迟期)肝实质回声、病灶变化(高增强、等增强、低增强)、增强模式(快进快出、快进等出、快进慢出、等进慢出),以及真假阳性例数。比较两组诊断的准确率、敏感度与特异度。结果研究组动脉期等增强占比低于对照组,而高增强占比高于对照组;研究组门脉期、延迟期低增强占比高于对照组,而等增强占比低于对照组(P<0.05)。研究组增强模式优于对照组,敏感度、特异度、准确率均高于对照组(P<0.05)。结论超声造影联合增强CT对肝局灶性结节与小肝细胞癌早期的临床鉴别诊断价值确切,有着较高的特异度、灵敏度以及准确度,值得临床应用。 Objective To analyze the clinical value of contrast-enhanced ultrasound combined with enhanced CT in the early differential diagnosis of focal liver nodules and small hepatocellular carcinoma.Methods A total of 60 patients with suspected focal hepatic nodules and small hepatocellular carcinoma admitted to Xingan County People's Hospital from January 2020 to August 2023 were selected as the research objects.According to the random number table method,all patients were divided into control group and study group,with 30 patients in each group.The control group was treated with enhanced CT,and the study group was treated with liver contrast-enhanced ultrasound on the basis of the control group.The echo of liver parenchyma,lesion changes(high enhancement,equal enhancement,low enhancement),enhancement mode(fast in fast out,fast in equal out,fast in slow out,equal in slow out)and the number of true and false positive cases were compared between the two groups at different stages(arterial phase,portal phase,delayed phase).The accuracy,sensitivity and specificity of the two groups were compared.Results The proportion of equal enhancement in the arterial phase of the study group was lower than that of the control group,while the proportion of high enhancement was higher than that of the control group;the proportion of low enhancement in portal venous phase and delayed phase in the study group was higher than that in the control group,while the proportion of equal enhancement was lower than that in the control group(P<0.05).The enhancement mode of the study group was better than that of the control group,and the sensitivity,specificity and accuracy were higher than those of the control group(P<0.05).Conclusion Contrast-enhanced ultrasound combined with enhanced CT is of great value in the early clinical differential diagnosis of focal liver nodules and small hepatocellular carcinoma.It has high specificity,sensitivity and accuracy,and is worthy of clinical application.
作者 黄志涛 周彩红 郭伟勤 HUANG Zhitao;ZHOU Caihong;GUO Weiqin(Department of Imaging,Xingan County People's Hospital,Xingan 331300,Jiangxi,China;Department of Obstetrics and Gynecology,Xingan Hospital of Traditional Chinese Medicine,Xingan 331300,Jiangxi,China)
出处 《医学信息》 2024年第22期161-164,共4页 Journal of Medical Information
关键词 超声造影 增强CT 肝局灶性结节 小肝细胞癌 早期 鉴别诊断 Contrast-enhanced ultrasound Enhanced CT Focal nodules of liver Small hepatocellular carcinoma Early stage Differential diagnosis
作者简介 黄志涛(1974.6-),男,江西新干县人,专科,主治医师,主要从事影像科诊断工作。
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