摘要
目的研究医院内孕妇尿路感染的病原菌分布特征及相关危险因素,为及时防控尿路感染提供科学指导。方法收集2019年1月至2023年12月广东省人民医院确诊的299例妊娠合并尿路感染孕妇为感染组,按照病例对照1∶1原则,随机选取同期诊断299例无尿路感染孕妇为对照组,对孕妇尿路感染病原菌分布特点及危险因素进行回顾性分析。结果感染组中检出革兰阳性菌占46.5%,革兰阴性菌占45.5%,真菌占8.0%;其中大肠埃希菌检出率最高(32.4%),其次为无乳链球菌(31.4%)和肺炎克雷伯菌(5.4%)。年龄、孕周、住院时间、流产史、个人尿路感染史和阴道炎是孕妇尿路感染的重要危险因素,孕周、流产史、个人尿路感染史和阴道炎是孕妇发生妊娠合并尿路感染的独立危险因素。结论孕妇尿路感染的因素相对较为复杂,孕周、流产史、个人尿路感染史和阴道炎是孕妇发生妊娠合并尿路感染的独立危险因素,临床可据此给予针对性的防治措施及抗菌治疗,以达到降低尿路感染风险的目的。
Objective To study distribution characteristics of pathogens and related risk factors of urinary tract infection in hospitalized pregnant women,and to further provide scientific guidance for timely prevention and control of urinary tract infections.Methods Adopting a case-control study in a 1∶1 ratio,a total of 299 pregnant women with urinary tract infections diagnosed in Guangdong Provincial People’s Hospital from January,2019 to December,2023 were defined as the infection group.Meanwhile,we randomly selected 299 cases of pregnant women without urinary tract infections as the control group.Characteristics of pathogen distribution and risk factors of urinary tract infections in pregnant women were analyzed retrospectively.Results In the infected group,46.5%were identified as Gram-positive bacteria,while 45.5%were Gram-negative bacteria,and 8.0%were fungi.Escherichia coli had the highest detection rate(32.4%),followed by Streptococcus agalactiae(31.4%)and Klebsiella pneumoniae(5.4%).Age,gestational age,length of hospital stay,abortion history,personal history of urinary tract infection and vaginitis were identified as important risk factors for pregnancy with urinary tract infections,while gestational age,abortion history,personal urinary tract infection history and vaginitis were independent risk factors for pregnant women with urinary tract infections.Conclusion Risk factors of urinary tract infections in pregnancy can be complicated,and gestational age,abortion history,personal history of urinary tract infection and vaginitis are independent risk factors of pregnancy and urinary tract infection in pregnant women.In order to reduce the risk level of urinary tract infections,effective preventions and anti-bacterial treatments should be applied accordingly.
作者
刘洁
蔡依含
禄梦笛
凌勇
周艳
赵铭鹏
白雪皎
LIU Jie;CAI Yihan;LU Mengdi;LING Yong;ZHOU Yan;ZHAO Mingpeng;BAI Xuejiao(Guangdong Provincial People’s Hospital(Guangdong Academy of Medical Sciences),Southern Medical University,Guangzhou 510080;Xiaolan People’s Hospital of Zhongshan,Zhongshan 528415,China)
出处
《标记免疫分析与临床》
CAS
2024年第10期1861-1864,共4页
Labeled Immunoassays and Clinical Medicine
基金
广东省医学科学技术研究基金项目(编号:A2023001)。
关键词
尿路感染
病原菌
危险因素
孕妇
Urinary tract infection
Pathogenic bacteria
Risk factors
Pregnant women
作者简介
刘洁。E-mail:liujie@gdph.org.cn;通讯作者:白雪皎。E-mail:baixuejiao@gdph.org.cn。
