摘要
中国病毒学家顾方舟,是中国组织培养口服减毒疫苗的开拓者,他的研究工作极大地提高了脊灰减毒疫苗的接种效果,使千百万儿童免受脊灰的威胁。以顾方舟为研究对象,介绍了顾方舟走上公共卫生和病毒学道路的原因以及研制中国首批“脊灰”减毒疫苗的过程等,讨论了影响脊灰疫苗技术路线选择的因素,以及疫苗的生产、检定、临床试验的过程与结果。
Gu Fangzhou's work has significantly improved the effectiveness of polio attenuated vaccine and protected millions of children from the threat of polio.As a pioneer in the development of China's oral attenuated vaccine through cell culture,Gu's journey into public health and virology is explored in this paper.The reasons behind Gu's pursuit of a career in public health and virology are introduced and the process of developing China's first batches of attenuated polio vaccines is detailed.Furthermore,the factors influencing the choice of technical routes for polio vaccine development is discussed,as well as the processes and results of vaccine production,verification,and clinical trials.Gu has closely linked his personal destiny with the future of the nation.His research and efforts have significantly improved the health and quality of life for hundreds of millions of people.
作者
左锟澜
黄剑良
孙博
刘欢
ZUO Kunlan;HUANG Jianliang;SUN Bo;LIU Huan(Department of History of Science and Scientific Archaeology,University of Science and Technology of China,Hefei 230026,China;Beijing University of Chinese Medicine Third Affiliated Hospital,Beijing 100029,China;State Key Laboratory of Virology,Wuhan 430072,China)
出处
《科技导报》
CAS
CSCD
北大核心
2024年第19期119-127,共9页
Science & Technology Review
基金
中国疾病预防控制中心项目(BB2110240080)
中国科学技术大学质量工程项目(2023XXSKC03,2023YCZX02)。
关键词
顾方舟
脊髓灰质炎
减毒疫苗
卫生健康
科技史
Gu Fangzhou
polio
attenuated vaccine
public health
history of science and technology
作者简介
左锟澜,硕士研究生,研究方向为科学技术史,电子信箱:nemo12@mail.ustc.edu.cn;通信作者:刘欢,副教授,研究方向为科学技术史、医学史、生命科学史,电子信箱:liuhuan520@ustc.edu.cn。
