摘要
目的了解福州市长乐区人民医院住院患者应用糖皮质激素的现状,评价处方合理性,为临床合理用药提供依据。方法随机选取2020年12月至2022年12月于福州市长乐区人民医院住院的550例接受糖皮质激素治疗的患者为研究对象,回顾性分析所有患者应用糖皮质激素的种类、疾病类型、剂量、科室及联合用药等情况,并对患者的基本资料进行统计,针对部分处方进行相应的合理性点评。结果布地奈德混悬液在使用类型中所占比例最高,达23.45%,其次为醋酸地塞米松片、地塞米松磷酸钠注射液和醋酸泼尼松片;疾病类型中以肺部感染为主,共134例,占比24.36%;其次是慢性肾功能衰竭、慢性阻塞性肺疾病、支气管哮喘、胆囊结石/胆囊炎;患者科室涉及儿科最多占19.09%,其次是重症监护室、心血管内科;患者年龄10岁以下最多,占35.64%,其次是65~80岁。本研究中不合理用药率较高,在不合理用药的统计结果中,以剂量不合理、联合用药不合理以及给药方式不合理占比较多。结论目前在住院患者中,糖皮质激素类药物的不合理应用情况仍然存在,因此需要加强医师的职业素质,加强用药的合理有效监督,以降低不合理用药的现象,提高医院整体合理用药水平。
Objective To investigate the current situation of glucocorticoid use in inpatients in our hospital,evaluate the rationality of its prescription,and provide evidence for clinical rational drug use.Methods 550 patients who received glucocorticoid therapy and were hospitalized in Fuzhou Changle District People’s Hospital from December 2020 to December 2022 were randomly selected as the study objects.The types,disease types,dosages,departments,and combination of glucocorticoids used in all patients were retrospectively analyzed,and the basic data of patients were statistically analyzed.And corresponding rational comments were made on some prescriptions.Results Budesonide suspension accounted for the highest proportion of 23.45%,followed by dexamethasone acetate tablet,dexamethasone sodium phosphate injection,and prednisone acetate tablet.Among the disease types,pulmonary infection was the main one,including 134 cases,accounting for 24.36%;Followed by chronic renal failure,chronic obstructive pulmonary disease,bronchial asthma,gallstones/cholecystitis;Pediatric patients were the most involved(19.09%),followed by intensive care unit and cardiovascular medicine.Patients under 10 years old accounted for the highest portion(35.64%),followed by 65-80 years old patients.The number of clinical irrational drug use in the 550 patients studied was high.Irrational drug use results were mostly irrational dosage,irrational combination of drug,and irrational drug administration mode.Conclusion At present,the irrational use of glucocorticoids still exists in the inpatients of our hospital,so it is necessary to strengthen the professional quality of doctors and strengthen the rational and effective supervision of drug use,so as to reduce the phenomenon of irrational drug use and improve the overall level of rational drug use in the hospital.
作者
郑琴
ZHENG Qin(Pharmacy Department of Changle District People's Hospital,Fuzhou 350200,China)
出处
《中华灾害救援医学》
2024年第5期516-519,共4页
Chinese Journal of Disaster Medicine
作者简介
通信作者:郑琴,E-mail:zhengqing123wz@163.com。
