摘要
目的探讨镇静剂量下咪达唑仑和地西泮对硬膜外麻醉手术的麻醉效果。方法方便选取单县中心医院于2022年1月—2023年12月收治的106例采取硬膜外麻醉手术的患者为研究对象,依据不同麻醉用药将患者分为研究组(咪达唑仑)与对照组(地西泮),各53例。比较两组患者的不良反应发生率、麻醉恢复指标、认知功能指标及生命体征变化。结果研究组不良反应总发生率(1.88%)低于对照组15.09%,差异有统计学意义(χ^(2)=4.371,P=0.037)。研究组麻醉起效时间(0.58±0.23)min、自主呼吸时间(3.24±0.18)min、意识恢复时间(180.12±10.25)min、气管拔管时间(20.12±2.65)min,均短于对照组的(0.74±0.51)、(4.21±0.21)、(189.62±10.18)、(25.23±2.34)min,差异有统计学意义(t=2.082、25.531、4.787、10.522,P均<0.05)。研究组认知功能指标、血压及血氧饱和度指标均优于对照组,差异有统计学意义(P均<0.05)。结论咪达唑仑麻醉药物镇静辅助效果更好,能够降低不良反应发生率,术后麻醉恢复速度更快,可降低对患者认知功能的影响,可稳定麻醉指标降低对患者血压及血氧饱和度的影响,辅助手术顺利进行。
Objective To investigate the anesthetic effect of midazolam and diazepam on epidural anesthesia and the influence of midazolam and diazepam on cortisol.Methods A total of 106 patients who underwent epidural anesthesia in Shanxian County Central Hospital from January 2022 to December 2023 were conveniently selected as the research objects.According to different anesthetic drugs,the patients were divided into study group(midazolam)and control group(diazepam),with 53 cases in each group.The incidence of adverse reactions,anesthesia recovery index,cogni-tive function index and vital signs were compared between the two groups.Results The total incidence of adverse reac-tions in the study group(1.88%)was lower than that in the control group(15.09%),and the difference was statistically significant(χ^(2)=4.371,P=0.037).The anesthesia onset time(0.58±0.23)min,spontaneous breathing time(3.24±0.18)min,consciousness recovery time(180.12±10.25)min,and tracheal extubation time(20.12±2.65)min in the study group were shorter than those in the control group(0.74±0.51)min,(4.21±0.21)min,(189.62±10.18)min,(25.23±2.34)min,the differences were statistically significant(t=2.082,25.531,4.787,10.522,all P<0.05).The cognitive function index,blood pressure and blood oxygen saturation index of the study group were better than those of the con-trol group,and the differences were statistically significant(all P<0.05).Conclusion Midazolam anesthesia has better sedative auxiliary effect,can reduce the incidence of adverse reactions,and faster recovery from postoperative anesthe-sia,can reduce the impact on patients'cognitive function,can stabilize anesthesia indicators and reduce the impact on patients'blood pressure and blood oxygen saturation,and can be widely used for the smooth implementation of auxiliary sur-gery.
作者
孙秋艳
秦美英
田玲玲
SUN Qiuyan;QIN Meiying;TIAN Lingling(Department of Anesthesiology,Shanxian Central Hospital,Heze 274300,Shandong,China)
出处
《中外医疗》
2024年第18期25-28,共4页
China & Foreign Medical Treatment
作者简介
孙秋艳(1980-),女,本科,主治医师,研究方向为临床麻醉学。
