摘要
目的 探讨社区获得性肺炎(community acquired pneumonia,CAP)患者联用抗生素和喜炎平注射液的治疗效果。方法 选取2022年7月—2023年6月曹县人民医院收治的90例CAP患者为研究对象,依照随机数表法分为研究组和对照组,每组45例。研究组患者采用喜炎平注射液与抗生素联合治疗,对照组仅采用抗生素治疗。对比两组疗效、症状与体征消退时间、炎症指标与不良反应发生情况。结果 研究组治疗总有效率(95.56%)高于对照组(80.00%),差异有统计学意义(χ^(2)=5.075,P<0.05)。研究组的咳嗽、啰音消退时间与退热时间均短于对照组,差异有统计学意义(P均<0.05)。研究组降钙素原、C反应蛋白水平低于对照组,差异有统计学意义(P均<0.05)。两组不良反应发生率对比,差异无统计学意义(P>0.05)。结论 CAP患者在抗生素治疗的基础上联用喜炎平注射液可以有效提高临床疗效,促进症状与体征恢复,改善炎症指标。
Objective To investigate the effect of combination of antibiotics and Xiyanping injection on patients with community acquired pneumonia (CAP).Methods A total of 90 patients with CAP admitted to Caoxian People's Hospital from July 2022 to June 2023 were selected as study objects and divided into study group and control group according to random number table method,45 cases in each group.Patients in the study group were treated with Xiyanping injection and antibiotics,while the control group was treated with antibiotics only.The curative effect,the time of symptom and sign resolution,inflammatory indexes and adverse reactions were compared between the two groups.Results The total effective rate in the study group (95.56%) was higher than that of the control group (80.00%),and the difference was statistically significant (χ^(2)=5.075,P<0.05).Compared with the control group,the study group had shorter time for cough and rales to subside and fever to subside,and the differences were statistically significant (all P<0.05).Compared with the control group,the study group had lower levels of procalcitonin and C-reactive protein,and the differences were statistically significant (both P<0.05).In the comparison of incidence of adverse reactions,there was no statistically significant difference between two groups (P>0.05).Conclusion Combined treatment with Xiyanping injection on the basis of antibiotics for CAP patients can effectively improve clinical efficacy,promote the recovery of symptoms and signs,and improve inflammatory indicators.
作者
李得震
宋雪薇
陶祥丹
LI Dezhen;SONG Xuewei;TAO Xiangdan(Department of Respiratory and Critical Care MedicineⅢ,Caoxian People's Hospital,Heze 274400,Shandong,China)
出处
《世界复合医学》
2024年第4期79-82,共4页
World Journal of Complex Medicine
关键词
喜炎平注射液
抗生素
社区获得性肺炎
Xiyanping injection
Antibiotics
Community acquired pneumonia
作者简介
李得震(1996-),男,本科,医师,研究方向为呼吸重症治疗。
