摘要
目的探讨中国药物相关问题分类系统在神经内科住院患者药学监护中的应用。方法选取2022年3—6月浙江大学医学院附属金华医院神经内科收治的222例住院患者为研究对象,回顾性分析临床药师工作记录。依照中国药物相关问题分类系统对药物相关问题(DRP)进行整理和分析。采用二项Logistic回归模型明确发生DRP的影响因素。结果222例患者中,有76例(34.23%)存在DRP,共识别出104个DRP。DRP主要问题类型为治疗安全性(39.42%)。DRP涉及对象均为医生,严重程度评估涉及最多的级别为“DRP到达了患者,但患者没有受到伤害”(81.73%)。DRP主要原因为“药物选择”(67.31%),其次为“用法用量”(26.92%)。共有62个(59.62%)DRP的介入方案被接受,介入方案总体接受率为87.32%。最终有61个(58.65%)DRP被解决。DRP涉及例次最多的药物类别为抗血小板药物。二项Logistic回归分析结果显示,用药品种数[OR=1.097,95%CI(1.030,1.167)]是神经内科住院患者发生DRP的影响因素(P<0.05)。结论神经内科住院患者DRP普遍存在。中国药物相关问题分类系统有助于临床药师对药学监护数据进行回顾和整理,总结共性问题和解决经验,提高药学监护效果。
Objective To explore the application of Chinese Drug-Related Problems Classification System in the pharmaceutical care of inpatients in neurology department.Methods A total of 222 inpatients admitted to the Department of Neurology of Affiliated Jinhua Hospital,Zhejiang University School of Medicine from March to June 2022 were selected as the study subjects,and the work records of clinical pharmacists were retrospectively analyzed.The drug-related problems(DRP)were sorted and analyzed according to the Chinese Drug-Related Problems Classification System.Binomial Logistic regression model was used to analyse the influencing factors of DRP.Results Among the 222 patients,76(34.23%)had DRP and a total of 104 DRP were found.The main problem type of DRP was treatment safety(39.42%).The involving objects of DRP were all doctors.In the severity assessment,the most involved level was“DRP reached the patient,but the patient was not harmed”(81.73%).The main reason for DRP was“choice of drugs”(67.31%),followed by“usage and dosage”(26.92%).A total of 62(59.62%)DRP intervention schemes were accepted,and the overall acceptance rate of intervention schemes was 87.32%.In the end,61(58.65%)DRPs were resolved.The drug class with the largest number of DRP cases was antiplatelet drugs.Binomial Logistic regression analysis showed that the number of drug varieties[OR=1.097,95%CI(1.030,1.167)]was the influencing factor for the occurrence of DRP in neurology inpatients(P<0.05).Conclusion DRP is common in inpatients of neurology department.Chinese Drug-Related Problems Classification System is helpful for clinical pharmacists to review and sort pharmaceutical care data,summarize common problems and solving experience,and improve the effect of pharmaceutical care.
作者
郭和坚
陈国权
朱亚兰
陈光明
陈红芳
陈刚
GUO Hejian;CHEN Guoquan;ZHU Yalan;CHEN Guangming;CHEN Hongfang;CHEN Gang(Department of Pharmacy,Affiliated Jinhua Hospital,Zhejiang University School of Medicine,Jinhua 321000,Zhejiang Province,China;Department of General Medicine,Affiliated Jinhua Hospital,Zhejiang University School of Medicine,Jinhua 321000,Zhejiang Province,China;Department of Neurology,Affiliated Jinhua Hospital,Zhejiang University School of Medicine,Jinhua 321000,Zhejiang Province,China;Department of Pharmacy,Dongtai People's Hospital,Dongtai 224200,Jiangsu Province,China)
出处
《中国药师》
CAS
2024年第7期1202-1209,共8页
China Pharmacist
基金
浙江省公益技术应用研究计划项目(2016C33228)
金华市科技局重点科技计划项目(2023-3-116)。
关键词
药物相关问题
中国药物相关问题分类系统
神经内科
药学监护
临床药师
Drug-related problems
Chinese Drug-Related Problems Classification System
Department of neurology
Pharmaceutical care
Clinical pharmacist
作者简介
通信作者:陈刚,硕士,副主任药师,Email:cg803315@126.com。
