摘要
目的:探讨生血宝合剂联合蔗糖铁和氨甲环酸对减少老年髋关节置换术围手术期失血的效果。方法:选取九江市第一人民医院骨科2022年9月—2024年3月收治的行人工髋关节置换术治疗的患者108例,以随机数字表法分成两组,各54例。其中对照组行常规血液管理方案(蔗糖铁+氨甲环酸),观察组在对照组基础上加用生血宝合剂。比较两组血常规指标[红细胞(RBC)、血红蛋白(Hb)、红细胞压积(HCT)]、失血量、输血量、输血率、中医症候积分、血栓及感染等不良事件。结果:术前两组RBC、Hb、HCT对比差异均无统计学意义(P>0.05);术后3 d和7 d,观察组RBC、Hb、HCT指标水平均高于对照组,差异均有统计学意义(P<0.05)。观察组失血量少于对照组,差异有统计学意义(P<0.05),观察组输血量、输血率均低于对照组,但差异均无统计学意义(P>0.05)。术前两组中医症候积分对比差异无统计学意义(P>0.05);术后2周观察组中医症候积分低于对照组,差异有统计学意义(P<0.05),治疗后观察组中医症候治疗总有效率为94.44%,高于对照组的79.63%,差异有统计学意义(P<0.05)。观察组深静脉血栓、感染等不良事件发生率为3.70%(2/54),对照组为5.56%(3/54),差异无统计学意义(P>0.05)。结论:生血宝合剂联合蔗糖铁、氨甲环酸可减少老年髋关节置换术患者围手术期失血量,控制输血量,能够改善围手术期患者的血常规指标,改善手术引起的气血两虚问题,并不会增加血栓、感染等不良事件的发生,获得更理想的手术治疗效果。
Objective:To investigate the effect of Shengxuebao Mixture combined with Iron Sucrose and Tranexamic Acid on reducing perioperative blood loss in elderly hip replacement.Method:A total of 108 patients admitted to the Department of Orthopedics at the Jiujiang NO.1 People's Hospital from September 2022 to March 2024 were selected.According to the random number table method,they were divided into two groups,54 cases in each group.The patients in the control group were used routine blood management solutions(Sucrose Iron+Tranexamic Acid),the patients in the observation group were used Shengxuebao Mixture on the basis of the control group.The blood routine indexes[red blood cell(RBC),hemoglobin(Hb),hematocrit(HCT)],blood loss,blood transfusion volume,blood transfusion rate,TCM syndrome score,thrombosis,infection and other adverse events were compared between the two groups.Result:Before operation,there were no significant differences in RBC,Hb and HCT between two groups(P>0.05);3 d and 7 d after operation,the level of RBC,Hb and HCT in the observation group were higher than those in the control group(P<0.05).The blood loss in the observation group was less than that of the control group,the difference was statistically significant(P<0.05),and the transfusion volume and transfusion rate of the observation group were lower than that of the control group,but the differences were not statistically significant(P>0.05).There was no statistically significant difference in TCM syndrome scores between the two groups before operation(P>0.05).Two weeks after operation,the TCM syndrome score of the observation group was lower than that of the control group,the difference was statistically significant(P<0.05).After treatment,the total effective rate of TCM syndrome treatment in the observation group was 94.44%,which was higher than 79.63%in the control group,the difference was statistically significant(P<0.05).Adverse events such as observation group of deep vein thrombosis,infection rate was 3.70%(2/54),the incidence of the control group was 5.56%(3/54),there was no statistically significant difference(P>0.05).Conclusion:Shengxuebao Mixture combined with Iron Sucrose and Tranexamic Acid can reduce the elderly hip arthroplasty patients with perioperative blood loss,control bleeding volume,can improve the patients with perioperative blood routine index,improve the Qi and blood deficiency problems caused by surgery,will not increase the occurrence of adverse events,such as thrombosis,infection,get more ideal surgical treatment effect.
作者
刘牧子
龚时国
谢荣辉
黄亚翔
张紫红
LIU Muzi;GONG Shiguo;XIE Ronghui;HUANG Yaxiang;ZHANG Zihong(Department of Orthopedics,Jiujiang NO.1 People's Hospital,Jiujiang 332000,China;不详)
出处
《中国医学创新》
CAS
2024年第19期16-20,共5页
Medical Innovation of China
基金
江西省中医药管理局科技计划项目(2023B1009)。
关键词
生血宝合剂
髋关节置换术
失血
血液管理
中医症候积分
Shengxuebao
Mixture Hip replacement
Blood loss
Blood management
Traditional
Chinese medicine syndrome score
作者简介
通信作者:张紫红。
