摘要
考察单煎、合煎和浸泡工艺制备的植物性露酒间的化学等量性和药效等效性。露酒组方中香源性物质分别采用复方浸泡、合煎和单煎三种方法提取,并制备成露酒,以常规功能成分、特征成分及高通量体外筛选,小鼠负重游泳试验和人体功能感知情况作为衡量指标,综合评定三种提取方法制备的露酒整体质量差异。单煎中黄酮、皂苷类、多糖类常规功能成分含量较高,分别达183.4, 738.3和5 314 mg/L,人参皂苷Re等特征成分含量较多;抗氧化、免疫调节和降尿酸等体外功能活性及“身体疲劳犯困、手脚冰凉、精神萎靡和睡眠质量”等人体功能改善效果显著。通过化学等量性和药效等效性综合等效性判定确认单煎工艺有利于该露酒组方香源性物质功能成分的溶出,提升功能效果。
To investigate the chemical equivalence and pharmaceutic equivalence of plant-based Lujiu prepared by single decoction, combined decoction, and soaking techniques, the aroma derived substances in the formula of Lujiu are extracted using three methods of compound soaking, combined decoction and single decoction, and are finally processed into Lujiu.The overall quality differences of Lujiu processed by the three extraction methods are evaluated using conventional functional components, characteristic components, high-throughput in vitro screening, mouse weight-bearing swimming test, and human functional perception as measurement indicators. The content of conventional functional components such as flavonoids,saponins, and polysaccharides in single decoction is relatively high, reaching 183.4, 738.3, and 5 314 mg/L, respectively.The content of characteristic components such as ginsenoside Re is relatively high;Antioxidation, immune regulation, uric acid lowering and other in vitro functional activities, as well as significant improves in human functions such as “fatigue and drowsiness, cold hands and feet, mental fatigue, and sleep quality”. Based on the comprehensive equivalence assessment of chemical equivalence and pharmaceutic equivalence, it is confirmed that the single decoction process is conducive to the dissolution of the functional components of the aroma source substances in the dew wine formula, thereby improving the product's functional effect.
作者
黄秀华
马丽娜
杨闻
李先芝
刘涛涛
王喆
HUANG Xiuhua;MA Lina;YANG Wen;LI Xianzhi;LIU Taotao;WANG Zhe(Jing Brand Co.,Ltd.,Huangshi 435000)
出处
《食品工业》
CAS
2024年第5期8-14,共7页
The Food Industry
基金
湖北省自然科学基金项目(2022CFB137)。
关键词
提取方法
露酒
化学等量性
药效等效性
extraction method
Lujiu
chemical equivalence
pharmaceutic equivalence
作者简介
通信作者:王喆。
