摘要
Prostate cancer(PCa)is considered as an age-related disease and accounts for the most prevalence of urinary malignancies in men.1 We previously analyzed the cellular landscape of tumor microenvironment in PCa patients,where we found that cancer-related fibroblasts might play an important role in tumorigenesis and the development of PCa and tumor-associated macrophage(TAM)could function synergistically with them.2 Thus,we further integrated single-cell and bulk RNA sequencing with meta-analysis to specify the prognostic effect of TAM on PCa and construct molecular subgroups and predictive index to guide clinical practice.
作者简介
Corresponding authors:Dechao Feng,Fax:+862885422451.E-mail addresses:fdcfenix@stu.scu.edu.cn;Corresponding authors:Ping Han,hanping@scu.edu.cn。
