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皮肤温度监测在胺碘酮致静脉炎风险预警中的应用研究

Effects of skin temperature monitoring in risk warning of amiodarone induced phlebitis
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摘要 目的分析皮肤温度变化与胺碘酮致静脉炎发生的相关性,探讨该指标监测在静脉炎预警中的应用价值。方法采用便利抽样法,于2021年2月—2023年1月选取郑州大学第一附属医院心血管内科应用胺碘酮治疗的254例患者为研究对象。观察皮肤相对温差与静脉炎发生的相关性。采用Kaplan-Meier生存曲线和COX比例风险回归模型比较不同皮肤相对温差与静脉炎的发生风险。结果皮肤相对温差与静脉炎发生呈正相关关系(P<0.01),预测静脉炎的皮肤相对温差最佳截断值为0.4℃,该指标受试者工作特征曲线下面积为0.708,95%置信区间(CI)为0.64~0.78,约登指数为0.353,灵敏度为74.47%,特异度为70.99%。以最佳截断值将患者分为低风险组与高风险组,高风险组静脉炎发生风险是低风险组的5.25倍[风险比(HR):5.25,95%CI:3.76~9.45,P<0.01]。结论皮肤温度监测能够较好地预测胺碘酮致静脉炎的发生,提醒医务人员应该密切注意穿刺点皮肤温度的变化,以便及早发现温度预警信号,防止静脉炎的发生。 Objective To analyze the correlation between skin temperature and amiodarone induced phlebitis,and explore the application value of this indicator monitoring in phlebitis warning.Methods From February 2021 to January 2023,convenience sampling was used to select 254 patients treated with amiodarone in the Department of Cardiovascular of the First Affiliated Hospital of Zhengzhou University.The correlation between relative skin temperature difference and the occurrence of phlebitis was observed.Kaplan-Meier survival curve and COX proportional hazards regression model were used to compare the risk of phlebitis with different relative skin temperature differences.Results There was a positive correlation between the relative skin temperature difference and the occurrence of phlebitis(P<0.01).The optimal cutoff value of relative skin temperature for predicting phlebitis was 0.4℃,with an area under the receiver operating characteristic curve of 0.708,a 95%confidence interval(CI)of(0.64,0.78),a Jordan index of 0.353,a sensitivity of 74.47%,and a specificity of 70.99%.Patients were divided into low-risk and high-risk groups using the optimal cutoff value,and the risk of phlebitis in the high-risk group was 5.25 times of that in the low-risk group[hazard ratio(HR):5.25,95%CI(3.76,9.45),P<0.01].Conclusions Skin temperature monitoring can effectively predict the amiodarone induced phlebitis.Medical and nursing staff should closely monitor skin temperature at the puncture site in order to detect temperature warning signals early and prevent the occurrence of phlebitis.
作者 黄峥 张阳 闫海艳 Huang Zheng;Zhang Yang;Yan Haiyan(Department of Cardiovascular,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450000,China)
出处 《中华现代护理杂志》 2024年第15期2047-2050,共4页 Chinese Journal of Modern Nursing
基金 河南省科技攻关计划(232102310173)。
关键词 静脉炎 胺碘酮 皮肤温度监测 风险预警 Phlebitis Amiodarone Skin temperature monitoring Risk warning
作者简介 通信作者:张阳,Email:543778712@qq.com。
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