摘要
目的:评价温针灸治疗原发性痛经的有效性和安全性。方法:根据PRISMA指南进行系统综述和荟萃分析。收集PubMed、Web of Science、EMBASE、Cochrane Library、中国知网、维普、万方、中国生物医学数据库自建库至2023年5月的随机对照试验。使用Review Manager 5.4对所有获得的数据进行分析。结果:温针灸治疗原发性痛经在提高临床疗效{风险比(RR)=1.21,95%置信区间(CI)[1.16,1.25],P<0.00001},改善阻力指数(RI){均数差(MD)=-0.14,95%CI[-0.19,-0.08],P<0.00001}、搏动指数(PI)(MD=-0.55,95%CI[-0.69,-0.40],P<0.00001)、β-内啡肽(β-EP){标准化均数差(SMD)=1.36,95%CI[0.90,1.82],P<0.00001}、痛经证候积分(MD=-1.82,95%CI[-2.77,-0.87],P=0.0002)、疼痛视觉模拟评分法(VAS)评分(MD=-1.16,95%CI[-1.48,-0.83],P<0.00001)方面的作用优于单独的常规治疗,并且在不良反应发生率(P=0.01)方面低于对照组。证据质量等级评价结果显示临床疗效为中级,其他多为低级。结论:温针灸治疗原发性痛经的疗效明确,并且具有一定的安全性。
Objective:To evaluate the effectiveness and safety of warming-needle moxibustion in the treatment of primary dysmenorrhoea.Methods:The systematic review and Meta-analysis were conducted according to PRISMA guidelines.Randomized controlled trials from the establishment time of the databases to May 2023 were collected from PubMed,Web of Science,EMBASE,Cochrane Library,CNKI,VIP,Wanfang,and China Biomedical Database.All the obtained data were analyzed by Review Manager 5.4.Results:Warming-needle moxibustion for primary dysmenorrhea has a better effect in in the treatment of enhancing clinical effects{risk ratio(RR)=1.21,95%confidence interval(CI)[1.16,1.25],P<0.00001},improving resistance index(RI){mean difference(MD)=-0.14,95%CI[-0.19,-0.08],P<0.00001},pulse index(PI)(MD=-0.55,95%CI[-0.69,-0.40],P<0.00001),β-endorphin(β-EP){standardized mean difference(SMD)=1.36,95%CI[0.90,1.82],P<0.00001},dysmenorrhea syndrome scores(MD=-1.82,95%CI[-2.77,-0.87],P=0.0002),and Visual Analogue Scale(VAS)scores of pain(MD=-1.16,95%CI[-1.48,-0.83],P<0.00001)when compared with routine treatment alone,and the incidence of adverse reactions was lower than that in the control group(P=0.01).The results of the evaluation of the quality of evidence showed that the clinical effect was intermediate,and most of the others were low.Conclusion:Warming-needle moxibustion for primary dysmenorrhea has a definite curative effect with certain safety.
作者
陈奕臻
王庆波
CHEN Yizhen;WANG Qingbo(The First Affiliated Hospital of Henan University of Chinese Medicine,Zhengzhou Henan 450000,China)
出处
《新中医》
CAS
2024年第8期139-147,共9页
New Chinese Medicine
基金
河南省中医药科学研究专项课题(2019JDZX2041,2021JDZY071)。
关键词
原发性痛经
温针灸
系统评价
GRADE评价
META分析
Primary dysmenorrhea
Warming-needle moxibustion
Systematic evaluation
GRADE assessment
Meta-analysis
作者简介
陈奕臻(1987-),女,医学硕士,主治医师,E-mail:yizhenchen1017@163.com;通信作者:王庆波(1972-),男,医学硕士,主任医师,E-mail:wqb22@163.com。
