摘要
脑卒中是一种急性脑血管疾病,具有高发病率、高死亡率及高致残率等特点。脑-肠轴在脑卒中患者肠道菌群调节中起着至关重要的作用;肠道菌群通过血压调节、免疫调控、炎症反应及神经调节等参与脑卒中的发生发展及预后。同时,微生态制剂、肠道菌群移植等为脑卒中防治提供了新的思路和方式。近年来,肠道菌群与脑卒中的相关研究备受关注,本文就肠道菌群在脑卒中发生发展及治疗中的研究进展进行综述。
Stroke is an acute cerebrovascular disease with characteristics of high morbidity,high mortality and high disability rate.The brain-gut axis plays a crucial role in regulating intestinal flora in stroke;the intestinal flora participates in the development and prognosis of stroke through blood pressure regulation,immune regulation,inflammatory response and nerve regulation.At the same time,microecological preparations and fecal microbiota transplantation provide new ideas and methods for the prevention and treatment of stroke.In recent years,the relationship between intestinal flora and stroke has attracted much attention.This article provides an overview of research progress of intestinal flora in the occurrence,development and treatment of stroke.
作者
盛佳洁
王慧星
李萌
Sheng Jiajie;Wang Huixing;Li Meng(The Second Clinical Medical College,Zhejiang Chinese Medical University,Hangzhou 310053,China;Department of Clinical Laboratory,Zhejiang Hospital,Hangzhou 310013,China)
出处
《心脑血管病防治》
2024年第3期40-44,共5页
CARDIO-CEREBROVASCULAR DISEASE PREVENTION AND TREATMENT
基金
浙江省公益技术应用项目(LGC22H200011)。
关键词
脑卒中
肠道菌群
微生态制剂
肠道菌群移植
Stroke
Intestinal flora
Microecological preparation
Fecal microbiota transplantation
作者简介
通信作者:李萌,Email:lmbcwan@163.com。