摘要
[目的]采用荟萃分析方法探讨体质对单髁置换术疗效的影响及安全性。[方法]计算机检索建库至2023年9月中国知网、万方、维普、中国生物医学文献数据库、PubMed、Embase、Cochrane Library、Web Of Science等文献,使用RevMan5.4对纳入文献进行荟萃分析。[结果]共纳入11篇文献,其中前瞻性研究3篇,回顾性研究8篇,均为高质量研究,共涉及3 624膝,其中肥胖组1 258膝,正常组2 366膝。荟萃分析结果显示,肥胖组与正常组在VAS评分、KSS评分、HSS评分及术后并发症发生率的差异无统计学意义(P>0.05)。但肥胖组OKS评分显著低于正常组(I^(2)=89%, MD=-2.99, 95%CI-5.18~-0.81,P=0.007),肥胖组术后关节活动度显著小于正常组(I^(2)=34%, MD=-3.38, 95%CI-4.32~-2.44, P<0.001),肥胖组术后翻修率显著高于正常组(I^(2)=23%, RR=1.51, 95%CI 1.06~2.14, P=0.02)。[结论]与正常体质人相比,肥胖患者行UKA仍可获得较好临床结果,但肥胖患者术后OKS评分和膝关节活动度低于正常体质患者,且肥胖者术后翻修率增加。
[Objective] To investigate the influence of body composition on outcome of unicompartmental knee arthroplasty by metaanalysis. [Methods] The literatures from CNKI, Wanfang, Weipu, China Biomedical Literature Database, PubMed, Embase, Cochrane Library and Web of Science were searched by computer untill September 2023, and meta-analysis of the included literatures was performed using RevMan 5.4. [Results] A total of 11 literatures were included, including 3 prospective studies and 8 retrospective studies, all of which were high quality studies, involving a total of 3 624 knees, including 1 258 knees in the obese group and 2 366 knees in the normal group. As results of meta-analysis, there were no statistically significant differences in VAS score, KSS score, HSS score and incidence of postoperative complications between the obese group and the normal group(P>0.05). However, the obese group was marked significantly lower postoperative OKS score(I^(2)= 89%, MD=-2.99, 95%CI-5.18~0.81, P=0.007), and significantly less postoperative knee range of motion(I^(2)=34%, MD=-3.38, 95%CI-4.32~-2.44, P<0.001), whereas significantly higher postoperative revision rate(I^(2)= 23%, RR=1.51, 95%CI 1.06~2.14, P=0.02) than the normal group. [Conclusion] Compared with those normal body composition, the obese patients do still obtain benefits from UKA, but with postoperative OKS score and knee joint motion inferior to the normal body composition patients, while increased postoperative revision surgery rate.
作者
祁正玺
乔晓红
尚晋
曹海生
王利兵
QI Zheng-xi;QIAO Xiao-hong;SHANG Jin;CAO Hai-sheng;WANG Li-bing(Shanxi Medical University,Taiyuan 030000,China;People's Hospital of Liliang City,Liliang 033000,China)
出处
《中国矫形外科杂志》
CAS
CSCD
北大核心
2024年第8期709-714,共6页
Orthopedic Journal of China
关键词
单髁置换术
体质
体重指数
疗效
荟萃分析
unicompartmental knee arthroplasty
body composition
body mass index
efficacy
meta-analysis
作者简介
祁正玺,在读硕士,研究方向:骨与关节疾病的临床与实验研究,(电话)18435910214,(电子信箱)18435910214@163.com;通信作者:乔晓红,(电话)13037071926,(电子信箱)13037071926@163.com。
