摘要
目的观察五仙方治疗骨折术后不愈合的临床疗效。方法将60例骨折术后不愈合患者随机分为2组,对照组30例予西医常规治疗,治疗组30例在对照组治疗基础上加五仙方治疗,服用3个月。比较2组临床疗效及患者肿胀消退时间、止痛时间、骨痂生长时间、住院时间、骨折愈合时间,比较2组治疗前后红细胞聚集指数、全血黏度(低切)、全血黏度(中切)、全血黏度(高切)、血浆黏度、红细胞比容、健康调查简表(SF-36)评分、功能独立性评价量表(FIM)评分。结果治疗组总有效率93.33%(28/30),对照组总有效率70.00%(21/30),治疗组总有效率高于对照组(P<0.05)。治疗组肿胀消退时间、止痛时间、骨痂生长时间、住院时间、骨折愈合时间均明显短于对照组(P<0.05)。治疗后,2组血液流变学指标红细胞聚集指数、全血黏度(高切)、全血黏度(中切)、全血黏度(低切)、血浆黏度、红细胞比容均低于本组治疗前(P<0.05),且治疗组均低于对照组(P<0.05)。治疗后,2组SF-36情感职能、生理功能、社会功能、活力评分及FIM评分均较本组治疗前升高(P<0.05),且治疗组均高于对照组(P<0.05)。结论五仙方治疗骨折术后不愈合效果显著,能有效消肿止痛,促进骨痂生长,加快骨折愈合,改善患者血液流变学指标以及生活质量。
Objective To investigate the effect of Wuxian Formula on postoperative healing.Methods Totally 60 patients with postoperative fracture nonunion were randomly assigned to treatment group(routine Western medicine[RWM],n=30)or control group(Wuxian Formula plus RWM,n=30).The swelling regression time,analgesic time,callus formation time,hospitalization time,fracture healing time,red cell aggregation(RCA),whole blood viscosity(WBV)(low,medium,and high shear),plasma viscosity(PV),red blood cell volume(RBV),36-item Short Form Health Survey(SF-36),Functional Independence Measure(FIM)were included as comparators.The curative effect was assessed.Results The overall effective rate in the treatment group was better than that in the control group(93.33%[28/30]vs 70.00%[21/30],[P<0.05],respectively).After treatment,the time to swelling regression,analgesic,callus formation,hospitalization,fracture healing were significantly shorter in the treatment group than in the control group(P<0.05).RCA,WBV(low,medium,and high shear),PV,RBV in the both groups were significantly decreased(P<0.05),which decreased notably in the treatment group compared with the control group(P<0.05).SF-36 scores(emotional function,physiological function,social function,vitality)and FIM scores in the both groups remarkably increased(P<0.05),the improvements in the treatment group were significantly better(P<0.05).Conclusion Wuxian Formula on postoperative healing has significant effects,which can effectively reduce swelling and relieve pain,promote callus growth,accelerate fracture healing,and improve hemorheological indicators and quality of life.
作者
邸振宇
赵海燕
赵凌燕
DI Zhenyu;ZHAO Haiyan;ZHAO Lingyan(Second Department of Orthopedics,the No.2 Hospital of Baoding,Baoding,Hebei 071000;Department of Orthopedics,Jizhong Energy Fengfeng Group General Hospital,Handan,Hebei 056200)
出处
《河北中医》
2024年第5期736-739,共4页
Hebei Journal of Traditional Chinese Medicine
基金
保定市科学技术研究与发展计划项目(编号:18ZF253)。
关键词
骨折
不愈合
中药疗法
Fracture nonunion
Traditional Chinese medicine therapy
作者简介
邸振宇(1971—),男,主治医师,学士。研究方向:骨外科学。