摘要
山楂酸是一种五环三萜类化合物,广泛存在于油橄榄和山楂等多种天然植物中。山楂酸具有抗肿瘤、抗炎、抗氧化、抗菌、心血管保护、神经保护等药理作用。针对山楂酸的药理活性研究进展及其作用机制进行综述,为其进一步开发和应用提供参考依据。
Maslinic acid is a pentacyclic triterpenoid that is widely found in natural plants such as olives and hawthorns.Maslinic acid has anti-tumor,anti-inflammation,anti-oxidation,antibacterial,cardiovascular protection,neuroprotection,and other pharmacological effects.In this paper,the research progress of pharmacological activities and the mechanism of action of maslinic acid were reviewed,which provides the basis for the development and utilization of maslinic acid in the future.
作者
张林晨
张小琴
张俊平
ZHANG Linchen;ZHANG Xiaoqin;ZHANG Junping(School of Pharmacy,Fujian University of Traditional Chinese Medicine,Fuzhou 350122,China)
出处
《药学实践与服务》
CAS
2024年第5期185-189,共5页
Journal of Pharmaceutical Practice and Service
基金
福建中医药大学高层次人才科研启动资金项目(X2019005)。
关键词
山楂酸
药理活性
作用机制
maslinic acid
pharmacological activity
mechanism of action
作者简介
张林晨,硕士研究生,研究方向:药物活性评价及技术,Email:zhlincen199@163.com;通信作者:张俊平,博士生导师,研究方向:中药药理与毒理,Email:jpzhang08@163.com。