摘要
目的总结非小细胞肺癌纵隔淋巴结转移的影像学评估现状,为临床采取合适的检查方法提供参考。方法以“非小细胞肺癌、淋巴结转移、影像学检查”为中文关键词,以“non-small cell lung cancer、lymph node metastasis、imaging examination”为英文关键词,系统检索PubMed及中国知网数据库2005-01-01-2022-12-31相关文献。纳入标准:(1)非小细胞肺癌淋巴结转移的研究现状;(2)各类影像学检查在非小细胞肺癌中的研究进展;(3)各类影像学检查在淋巴结转移中的研究进展。排除标准:(1)数据陈旧文献;(2)相关性较低文献。最终纳入39篇文献进行分析。结果纵隔淋巴结有无转移决定着非小细胞肺癌后续治疗方案制定,各类影像学检查在其诊断及预测中均存在各自的优势,但仍面临着一些不足,如计算机体层成像检查准确度有限,正电子发射断层显像/计算机断层扫描费用较高,磁共振成像的优势临床认识不足,超声支气管镜因解剖结构关系存在漏诊可能性,影像组学研究较少。结论现有的影像学检查方法在非小细胞肺癌纵隔淋巴结转移的诊断及预测方面可为临床提供一定指导,多种方法联合、优势互补是未来重要的发展方向。
Objective To summarize the current status of imaging evaluation of mediastinal lymph node metastasis in non-small cell lung cancer,in order to provide some guidance for clinical examination.Methods Using PubMed database and China National Knowledge Infrastructure(CNKI)retrieval system.The relevant literature from January 1,2005 to December 31,2022 was searched with the keywords"non-small cell lung cancer,lymph node metastasis,imaging examination".Inclusion criteria were as follows:(1)Research status of lymph node metastasis in non-small cell lung cancer;(2)Research progress of various imaging examinations in non-small cell lung cancer;(3)Research progress of various imaging examinations in lymph node metastasis.The exclusion criteria:(1)Outdated data;(2)Low correlation literature.Finally,39 articles were included for analysis.Results The presence or absence of mediastinal lymph node metastasis determines the formulation of follow-up treatment options for non-small cell lung cancer.Various imaging examinations have their own advantages in their diagnosis and prediction,but they still face some deficiencies:the accuracy of computed tomography is limited;the cost of positron emission tomography/computed tomography is high;the clinical understanding of the advantages of magnetic resonance imaging is insufficient;endobronchial ultrasonography has the possibility of missed diagnosis due to anatomical structure;there are few studies on radiomics.Conclusions The existing imaging methods can provide some guidance for the diagnosis and prediction of mediastinal lymph node metastasis in non-small cell lung cancer.The combination of multiple methods and complementary advantages is an important development direction in the future.
作者
李悦
夏熙婷
周永
LI Yue;XIA Xiting;ZHOU Yong(Diagnostic Imaging Center,Affiliated Tumor Hospital of Xinjiang Medical University,Urumqi,Xinjiang 830011,China)
出处
《中华肿瘤防治杂志》
CAS
北大核心
2024年第1期53-57,共5页
Chinese Journal of Cancer Prevention and Treatment
作者简介
第一作者:李悦,女,陕西三原人,主要从事肿瘤影像诊断的临床研究工作。E-mail:2321930184@qq.com;通信作者:周永,男,新疆奎屯人,硕士,主任医师,主要从事肿瘤影像诊断的临床研究工作。E-mail:332090635@qq.com。
