摘要
目的探讨介入诊疗术式对恶性梗阻性黄疸(MOJ)肝功能的影响。方法选取2019年1月至2022年12月张家界市人民医院收治的50例恶性梗阻性黄疸患者作为研究对象,按照治疗方法不同分为对照组(n=24)与研究组(n=26)。对照组采用胆汁引流术包括经皮经肝胆道引流术(PTCD)或经皮经肝胆道支架术(PTBS),研究组行肝动脉化疗栓塞(TACE)。比较两组肝功能指标及并发症发生率。结果治疗后,两组谷草转氨酶(AST)、丙转氨酶(ALT)、总胆红素(TBIL)水平均低于治疗前,且研究组低于对照组,差异有统计学意义(P<0.05)。两组不良反应发生率比较差异无统计学意义。结论TACE治疗可改善患者肝功能,且不会增加患者不良反应发生。
Objective To investigate the effect of interventional diagnosis and treatment on liver function in patients with malignant obstructive jaundice(MOJ).Methods 50 patients with malignant obstructive jaundice admitted to Zhangjiajie People's Hospital from January 2019 to December 2022 were selected as the research subjects,they were divided into the control group(n=24)and the study group(n=26)according to different treat-ment methods.The control group was treated with bile drainage,including percutaneous transhepatic cholangial drainage(PTCD)or percutaneous transhepatic biliary stent(PTBS),and the study group was treated with transcatheter arterial chemoembolization(TACE).The liver function indexes and incidence of complications were compared between the two groups.Results After treatment,aspartate aminotransferase(AST),alanine amino-transferase(ALT)and total bilirubin(TBIL)in the two groups were lower than those before treatment,and those in the study group were lower than the control group,the differences were statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions be-tween the two groups.Conclusion TACE treatment can improve the liver function of patients without increasing the incidence of adverse reactions.
作者
王连峰
张鼎
唐沅莉
WANG Lianfeng;ZHANG Ding;TANG Yuanli(Department of Oncology,Zhangjiajie People's Hospital,Zhangjiajie,Hu'nan,437000,China)
出处
《当代医学》
2023年第30期165-168,共4页
Contemporary Medicine
关键词
恶性梗阻性黄疸
介入治疗
肝功能
Malignant obstructive jaundice
Interventional therapy
Liver function
