摘要
目的旨在研究克州地区高血脂患者药物干预血脂水平的时空演变规律,以期为临床治疗提供科学依据。方法选择2021年1月-2021年12月克孜勒苏柯尔克孜自治州人民医院收治的100例高脂血症患者,随机数字表法将患者分为两组,对照组(50例)接受常规调脂治疗,干预组(50例)接受调脂治疗和药学干预。比较两组调脂达标率、血脂水平、服药依从性、疾病认知以及不良反应的差异。结果通过对数据的统计分析,发现高血脂患者在药物干预后的血脂水平呈现出明显的时空演变规律。具体来说,在短期内(3个月),高血脂患者的血脂水平得到了显著的改善;而在长期内(6个月-1年),高血脂患者的血脂水平则呈现出波动性变化的特点。此外,我们还发现不同药物对高血脂患者的治疗效果存在差异,需要根据患者的具体情况进行个性化治疗。结论对于指导临床医生制定个性化的治疗方案具有重要的意义。同时,也为进一步探索高血脂患者药物治疗的效果提供了新的思路和方法。
Objective The aim of this study was to investigate the spatio-temporal evolution of drug intervention on blood lipid level in patients with hyperlipidemia in Kezhou area,so as to provide scientific basis for clinical treatment.Methods 100 patients with hyperlipidemia in the people's Hospital of Kizilsu Kirgiz Autonomous Prefecture from January 2021 to December 2021 were selected and randomly divided into two groups.The control group(50 cases)received conventional lipid-lowering therapy,and the intervention group(50 cases)received lipid-lowering therapy and pharmaceutical intervention.The differences in the rate of lipid regulation,blood lipid level,medication compliance,disease cognition and adverse reactions between the two groups were compared.Results Through the statistical analysis of the data,we found that the blood lipid level of patients with hyperlipidemia after drug intervention showed an obvious temporal and spatial evolution rule.Specifically,in the short term(3 months),the blood lipid level of patients with hyperlipidemia had been significantly improved;In the long term(6 months to 1 year),the blood lipid levels of patients with hyperlipidemia showed the characteristics of fluctuating changes.In addition,we also found that different drugs have different therapeutic effects on patients with hyperlipidemia,and personalized treatment should be carried out according to the specific situation of patients.Conclusion The results of this study are of great significance for guiding clinicians to formulate personalized treatment plans.At the same time,this study also provides new ideas and methods for further exploring the effect of drug treatment in patients with hyperlipidemia.
作者
万庆
赖德彬
WAN Qing;LAI Debin(Inspection Center,People's Hospital of Xinjiang Kezhou,Kezhou,Xinjiang,845350,China;Department of Pharmacy,People's Hospital of Xinjiang Kezhou,Kezhou,Xinjiang,845350,China)
出处
《新疆医学》
2024年第1期17-20,共4页
Xinjiang Medical Journal
基金
新疆维吾尔自治区自然科学基金面上项目(项目编号:2021D01A30)。
关键词
高脂血症
药物干预
血脂水平
时空演变
Hyperlipidemia
Drug intervention
Blood lipid level
Spatio temporal evolution
作者简介
万庆,男,副主任检验师,研究方向:医学检验;通信作者:赖德彬,女,副主任药师,研究方向:临床药学,E-mail:ldb123ldb@163.com。
