摘要
影像组学是一种新兴的诊疗技术,可以从CT、MR以及PET图像中高通量提取影像组学特征并筛选出与诊疗目的密切相关的特征,对肿瘤或疾病分型、预后或者基因组改变精准预测。Ki-67是一种细胞核蛋白,只存在于增殖分裂中的细胞核,在静止期的细胞核中不表达,因此可以作为细胞增殖能力的预测指标,已被证实与肺癌预后密切相关。本文就Ki-67在肺癌中的作用机制及其影像组学研究进展进行综述。
Radiomics is a new diagnostic and treatment technology,which can be employed to extract high-throughput radiomics features from CT,MR,and PET images and screen features closely related to diagnostic and treatment purposes,so as to accurately predict tumor or disease classification,prognosis,or genomic changes.Ki-67 is a type of nuclear protein,which is present only in nuclei of proliferative and dividing cells but not in those of quiescent phase cells;hence,it can be used as a predictor of cell proliferation and has been proven to be closely related to prognosis of lung cancer.This article reviews the mechanism and progress in radiomics research related to Ki-67 in lung cancer.
作者
魏宇泽
卢再鸣
任莹
WEI Yuze;LU Zaiming;REN Ying(Department of Radiology,Shengjing Hospital of China Medical University,Shenyang 110004,China)
出处
《中国医科大学学报》
CAS
北大核心
2024年第3期271-275,共5页
Journal of China Medical University
基金
国家自然科学基金(81771947)。
作者简介
魏宇泽(1997-),男,硕士研究生;通信作者:任莹,E-mail:renyingdyzh@sina.com。
