摘要
皮肤是覆盖人体表面并直接接触外部环境的一个非常重要的器官,皮肤伤口的修复是一个复杂而有序的过程。寻求促进创伤修复、具有优良性能的伤口敷料是目前的研究热点。水凝胶由于含水量高、生物相容性好、吸收渗出物、易于去除、提供湿润环境,在伤口敷料领域得到广泛的研究和应用。介绍了水凝胶的制备方法,总结了抗菌、止血、消炎、促组织再生等功能化水凝胶伤口敷料的研究进展,展望了水凝胶伤口敷料未来的发展方向。
Skin is a very important organ that covers the surface of human body and directly contacts the external environment.The repair of skin wounds is a complex and orderly process.Seeking wound dressings that can promote wound repair and have excellent performance is a current research hotspot.Hydrogels have been extensively studied and applied in the field of wound dressings due to their high water content,good biocompatibility,absorption of exudates,ease of removal,and provision of a moist environment.In this paper,we introduce the preparation method of hydrogels,and summarize the research progress of functionalized hydrogel wound dressings,including antibacterial,hemostasis,anti-inflammatory,and tissue regeneration.Moreover,we put forward the prospects in the future development direction of hydrogel wound dressings.
作者
肖陈然
沈陟
康顺吉
沈喜洲
XIAO Chenran;SHEN Zhi;KANG Shunji;SHEN Xizhou(College of Post and Telecommunication of Wuhan Institute of Technology,Wuhan 430073,China;College of Chemical Engineering and Pharmacy,Wuhan Institute of Technology,Wuhan 430205,China)
出处
《化学与生物工程》
CAS
北大核心
2024年第4期18-24,共7页
Chemistry & Bioengineering
基金
国家自然科学基金面上项目(51773159)。
关键词
水凝胶伤口敷料
抗菌
止血
消炎
组织再生
hydrogel wound dressing
antibacterial
hemostasis
anti-inflammatory
tissue regeneration
作者简介
肖陈然(1997-),男,湖北天门人,硕士研究生,研究方向:伤口敷料,E-mail:1098013063@qq.com;通讯作者:康顺吉(1983-),女,博士,副教授,研究方向:绿色石油化工和纳米材料,E-mail:316174056@qq.com。