摘要
目的 对本地区2022年7月至2023年6月来我院健康查体的周岁内婴幼儿维生素D营养状况和差异进行比较分析。方法 选取2022年7月至2023年6月来我院健康查体的周岁内,无急、慢性疾病的婴幼儿作为研究对象。取受试儿童末梢血,利用荧光免疫层析法对其血液中的总维生素D和25-羟基维生素D_(3)进行检测,并对数据进行分析和比较。结果 本地区周岁内婴幼儿整体维生素D营养状况良好,3/4婴幼儿维生素D为理想水平,维生素D缺乏者占比小于1.3%,且无严重缺乏者。随月龄增大,维生素D理想水平的婴幼儿比例减低,维生素D充足和缺乏的婴幼儿比例增加。整体婴幼儿和男、女婴幼儿在周岁内总维生素D和25-羟基维生素D_(3)的平均值均随着月龄增加而呈现小幅波动,且不同月龄的总维生素D、25-羟基维生素D_(3)在整体和女婴幼儿中均存在差异(P<0.001)。除3月龄外,各月龄男、女婴幼儿的总维生素D、25-羟基维生素D_(3)及其差值、比值均无差异。半岁前,男、女婴幼儿的总维生素D和25-羟基维生素D_(3)的平均值从2月龄开始每两个月进行翻转,半岁后,整体呈每月翻转。结论 本地区周岁内婴幼儿总体维生素D营养状况良好,但仍需加强婴幼儿维生素D的合理补充。
Objective To compare and analyze the nutritional status and differences of vitamin D in infants who underwent a physical exam in our hospital from July,2022 to June,2023.Methods Infants who visited our hospital for physical examination without acute or chronic diseases from July,2022 to June,2023 were selected as the study objects.Peripheral blood was taken and total vitamin D and 25-hydroxyvitamin D_(3)[25(OH)D_(3)]were detected by fluorescence immunochromatography.Datasets were then analyzed and compared.Results The overall vitamin D nutritional status of infants was relatively good in local region:3/4 of infant vitamin D were ideal level,and less than 1.3%infants showed vitamin D deficiency and no serious deficiency was observed.With age increasing,the proportion of infants with ideal vitamin D decreased,vitamin D sufficiency and deficiency increased.The average values of total vitamin D and 25-hydroxyvitamin D_(3) in total infants,as well as boys and girls showed slight fluctuation with age increasing,and the total vitamin D,25-hydroxyvitamin D_(3) showed significant differences among different month age in total infants and girl group(P<0.001).There was no difference in the total vitamin D,25-hydroxyvitamin D_(3),ratio in boy and girl groups at each months of age,except for 3 months.Before half a year old,the average values of total vitamin D,25-hudroxyvitamin D_(3) in boy and girl groups were reversed every two months from 2-month age.After that,the average values flipped monthly.Conclusion The overall vitamin D nutrition of infants up to one year old in local region is good.However,strengthen rational vitamin D supplement is necessary.
作者
谢杰施
陈怡菲
王殊
曹正
翟燕红
XIE Jieshi;CHEN Yifei;WANG Shu;CAO Zheng;ZHAI Yanhong(Department of Laboratory Medicine,Beijing Obstetrics and Gynecology Hospital,Capital Medical University,Beijing Maternal and Child Health Care Hospital,Beijing 10026,China)
出处
《标记免疫分析与临床》
CAS
2024年第1期16-21,47,共7页
Labeled Immunoassays and Clinical Medicine
基金
北京市属医院科研培育计划项目(编号:PX2020060)。
作者简介
谢杰施(1983—),女,博士研究生,初级技师,主要研究方向:妇产科疾病相关研究;通讯作者:翟燕红(1975—),女,本科,主任技师,E-mail:zhaiyanhong2006@ccmu.edu.cn。
