摘要
目的探讨经鼻高流量氧疗(HFNC)在老年支气管扩张伴呼吸衰竭患者辅助治疗中的应用效果。方法选取2020年8月至2021年1月南昌三三四医院呼吸科收治的60例支气管扩张伴呼吸衰竭患者作为研究对象,根据随机数字表法分为对照组与观察组,每组30例。对照组给予常规治疗,观察组在对照组基础上辅以HFNC治疗,比较两组短期临床疗效、血气指标、痰液黏稠度、痰液引流量、呼吸困难症状评分、住院时间。结果观察组治疗总有效率为93.33%,高于对照组的80.00%,但两组比较差异无统计学意义。两组血氧饱和度(SaO_(2))水平组间、时间、交互和氧分压(PO_(2))水平组间、时间及二氧化碳分压(PCO_(2))水平时间比较差异有统计学意义(P<0.05),PO_(2)水平交互和PCO_(2)水平组间、交互比较差异无统计学意义。治疗后6、12h,两组PO_(2)、SaO_(2)水平均高于前一时间点,PCO_(2)水平均低于前一时间点,且观察组PO_(2)、SaO_(2)水平均高于对照组,差异有统计学意义(P<0.05),两组PCO_(2)水平比较差异无统计学意义。治疗72h后,两组痰液黏稠度评分、Borg评分均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05);观察组痰液引流量多于对照组,住院时间短于对照组,差异有统计学意义(P<0.05)。结论HFNC应用于老年支气管扩张伴呼吸衰竭中,能有效促进排痰、改善患者氧合,缓解呼吸衰竭,在增强临床治疗效果的同时缩短治疗周期。
Objective To explore the application effect of high-flow nasal cannula oxygen therapy(HFNC)in elderly patients with bronchiecta-sis and respiratory failure.Methods 60 patients with bronchiectasis and respiratory failure admitted to the Respiratory department of Nanchang No.334 Hospital from August 2020 to January 2021 were selected as the study subjects,they were divided into the control group and the observation group according to the random number table method,with 30 cases in each group.The control group received conventional treatment,while the ob-servation group received HFNC treatment on the basis of the control group,the short-term clinical efficacy,blood gas indicators,sputum viscosity,sputum drainage volume,respiratory distress symptom scores,and hospital stay were compared between the two groups.Results The total effective rate in the observation group was 93.33%,which was higher than 80.00%in the control group,but there was no statistically significant difference be-tween the two groups.There were significant differences in the saturation of oxygen demand(SaO_(2))level between the two groups of intergroup,time points,and interaction,and partial pressure of oxygen(PO_(2))level between the group of intergroup,time points,partial pressure of carbon dioxide(PCO_(2))level between the two groups of time points(P<0.05),and there were no significant differences in PO_(2) level between the group of interaction and PCO_(2) level between the groups and interation.At 6 and 12 h after treatment,the levels of PO_(2) and SaO_(2) of the two groups were higher than those at the previous time point,and the levels of PCO_(2) were lower than those at the previous time point,and the levels of PO_(2) and SaO_(2) in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05),there was no statistically significant dif-ference in the levels of PCO_(2) between the two groups.After 72 h of treatment,the viscosity score and Borg score of sputum of the two groups were lower than before treatment,and the observation group was lower than the control group,and the differences were statistically significant(P<0.05).The sputum drainage volume in the observation group was higher than that in the control group,and the hospital stay was shorter than that in the control group,and the differences were statistically significant(P<0.05).Conclusion The application of HFNC in elderly patients with bronchiec-tasis and respiratory failure can effectively promote sputum excretion,improve patient oxygenation,relieve respiratory failure,improve clinical treat-ment effectiveness,and shorten treatment cycle.
作者
邓雪颖
高洁
黄良
DENG Xueying;GAO Jie;HUANG Liang(Department of Respiratory Medicine,Nanchang No.334 Hospital,Nanchang,Jiangxi,330024,China)
出处
《当代医学》
2023年第36期83-87,共5页
Contemporary Medicine
基金
江西省卫健委课题(202140116)。
关键词
经鼻高流量氧疗
支气管扩张
呼吸衰竭
血气指标
High-flow nasal cannula oxygen therapy
Bronchiectasis
Respiratory failure
Blood gas index
