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三位一体化协同急救在儿童暴发性心肌炎救治中的应用

Application of "trinity" synergistic emergency in the cure and treatment of children with fulminant myocarditis
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摘要 目的 观察三位一体化协同急救在儿童暴发性心肌炎(FM)救治中的应用效果。方法 回顾性分析常规急救护理的FM患儿和三位一体化协同急救FM患儿的资料,分别设为对照组和观察组,每组42例。比较2组并发症、体外膜肺氧合(ECMO)撤机率、病死率、干预前后的心肌损伤标志物(天门冬氨酸氨基转移酶及乳酸脱氢酶)及心功能情况(左室射血分数),调查2组家属的护理满意度。结果 观察组并发症总发生率低于对照组,ECMO撤机率高于对照组,差异有统计学意义(P<0.05);干预后,2组血清天门冬氨酸氨基转移酶及乳酸脱氢酶水平低于干预前,且观察组低于对照组,差异有统计学意义(P<0.05);2组左室射血分数高于干预前,且观察组高于对照组,差异有统计学意义(P<0.05);观察组家属的护理满意度高于对照组,差异有统计学意义(P<0.05)。结论 三位一体化协同急救应用于儿童FM中,能减少并发症,提高ECMO撤机率,改善心肌损伤和心功能,提高家属护理满意度。 Objective To observe the application effect of "trinity" synergistic emergency in the cure and treatment of children with fulminant myocarditis(FM).Methods Clinical materials of FM children with routine emergency nursing(control group) and FM children with "trinity" synergistic emergency(observation group) were retrospectively analyzed,with 42 cases in each group.The complications,weaning rate of extracorporeal membrane oxygenation(ECMO),mortality,myocardial injury markers(aspartate aminotransferase and lactate dehydrogenase) and cardiac function(left ventricular ejection fraction) before and after intervention were compared between the two groups,and the satisfaction degree to nursing of family members in both groups was investigated.Results The total incidence rate of complications in the observation group was lower than that in the control group(P<0.05),while the weaning rate of ECMO was higher than that in the control group(P<0.05);after intervention,serum levels of aspartate aminotransferase and lactate dehydrogenase in both groups were lower than those before intervention,and the levels of the two indexes in the observation group were significantly lower than those in the control group(P<0.05);the left ventricular ejection fraction in both groups was significantly higher than that before intervention,and the index in the observation group was higher than that in the control group(P<0.05);the satisfaction degree to nursing of family members in the observation group was significantly higher than that in the control group(P<0.05).Conclusion For children with FM,"trinity" synergistic emergency can reduce the complications,increase the weaning rate of ECMO,improve the myocardial injury and cardiac function,and increase the satisfaction degree to nursing of family members.
作者 刘云霞 陈梅 陈瑜 LIU Yunxia;CHEN Mei;CHEN Yu(Department of Cardiovascular Medicine,the Children′s Hospital Affiliated to Nanjing Medical University,Nanjing,Jiangsu,210019)
出处 《实用临床医药杂志》 CAS 2024年第4期92-96,101,共6页 Journal of Clinical Medicine in Practice
基金 国家自然科学基金资助项目(82100779)。
关键词 三位一体化协同急救 儿童暴发性心肌炎 并发症 体外膜肺氧合撤机率 心肌损伤标志物 心功能 "trinity"synergistic emergency fulminant myocarditis in children complications weaning rate of extracorporeal membrane oxygenation myocardial injury markers cardiac function
作者简介 通信作者:陈瑜,E-mail:786985550@qq.com。
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